摘要
目的利用颈动脉超声评价不同糖代谢人群中动脉内膜中层厚度(IMT)的变化及主要危险因素。方法将西宁地区健康体检人群中随机选择正常糖耐量者160例作为对照组,体检人群中筛选出糖调节受损者175例为观察组,其中空腹血糖受损(IFG)52例,糖耐量受损(IGT)91例,IFG+IGT者14例,2型糖尿病18例,其中合并高血压患者4例。测量血压、身高及体重,血清总胆固醇、空腹胰岛素、空腹与负荷后血糖。应用美国惠普5500超声诊断仪,观察各组动脉内膜及中层状况,以所测最大IMT及斑块发生率为观察指标。结果观察组双侧颈动脉、股动脉、斑块形成显著高于对照组(P<0．05),大血管损害随糖代谢的恶化而加重,合并高血压者最重。结论年龄、餐后高血糖、血压与老年人大血管损害密切相关。
Objective To investigate whether early carotid atherosclerosis indicated by change in intima-media thickness（IMT） is different among different glucose metabolism states.Methods 160 normal control subjects and 157 persons with impaired glucose regulation （IGR） were selected randomly from habitants of Xining prefecture. Of the IGR persons,52 had impaired fasting glucose （IFG）, 91 impaired glucose tolerance（IGT）, 14 IFG ＋ IGT and 18 diabetics, of whom,4 had hypertension. IMT of CCA and ICA was measured using B-mode colored Doppler ultrasonography. Results Compared with normal group, the CCA-IMT value was significantly increased in IGT plus IFG group （ P 〈 0.05） ,with significant difference. The ICA- IMT values showed difference between IFG ＋ IGT and normal groups. Conclusion Age, postprandial hyperglycemia and hypertension are closely related to lesions of big vessels in the elderly.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2007年第3期170-172,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
颈动脉疾病
葡萄糖代谢障碍
高血压
超声检查
多普勒
彩色
危险因素
carotid artery diseases
glucose metabolism disorders
hypertension
ultrasonography, Doppler, color
risk factors
