摘要
胆管癌的浸润和转移具有其自身的特点,经淋巴转移是胆管癌的主要转移方式之一,以局部淋巴结转移为主,较少发生远处转移.由于胆管的解剖部位的特点以及其与周围神经、包括多种神经肽的密切关系,其神经周围浸润转移途径近年来越来越受到人们的重视.除浸润转移、种植转移、淋巴道及血道转移等途径之外,经神经周围浸润和转移是胆管癌的一种重要病理特征,对胆管癌细胞与神经纤维的相互作用机制以及胆管癌神经周围浸润转移过程的调控因子的研究是近年的研究热点之一.
Invasion and metastasis of cholangiocarcinoma have specific characteristics. Lymph node metastasis is one of the metastatic modes of cholangiocarcinoma, and local metastasis occurs more frequently than distal one. Due to the specific anatomic structure of bile duct and its close relation with peripheral nerves and various neuropeptides, perineural invasiveness and metastasis of cholangiocarcinoma are attracting more and more attention in recent years. Besides invasive metastasis, inoculation metastasis, lymphatic metastasis and vascular metastasis, perineural invasiveness and metastasis are important pathological features of cholangiocarcinoma. Study on the mechanism, of interaction between nerve fiber and cholangiocarcinoma cells and the regulatory factors during invasion and metastasis of cholangiocarcinoma is one of the hot spots in recent years.
出处
《世界华人消化杂志》
CAS
北大核心
2007年第3期276-281,共6页
World Chinese Journal of Digestology
关键词
胆管癌
浸润
转移
Cholangiocarcinoma
Invasion
Metastasis
