摘要
目的评估肝门部胆管癌的病理特征对术后生存的影响并为临床治疗提供依据。方法回顾性分析1997年1月至2002年12月我院肝胆外科113例手术切除的肝门部胆管癌病理资料,并结合随访结果进行统计分析。结果高分化腺癌18例、中分化腺癌38例,低分化腺癌38例,黏液腺癌4例,其他类型15例。高、中、低分化腺癌术后5年生存率分别为57.0%,10.9%,18.8%,高分化与中低分化组间比较差异有显著性(P<0.05)。浸润能力高分化腺癌最弱、中低分化腺癌较强,黏液腺癌最强。分化程度,淋巴结转移、神经转移对术后生存时间均有显著影响(P<0.05)。结论肝门部胆管癌的分化程度、淋巴转移是影响预后的重要因素,神经转移对预后的影响仍需深入研究。
Objective To evaluate the effects of pathological characteristics on the postoperative survival in patients wish hilar choangioearcinoma （HCC）. Methods Clinical and pathological data of 113 cases of HCC in our hospital from January 1997 to December 2002 were collected and analyzed. Results There were 18, 38 and 38 cases of well-, medium and poor- differentiated adenoma, respee tively. There were 4 cases of mucus adcnoma and 15 cases of other pathologic type. The 5-year survival rate of well-, medium-, poor- differentiated adenoma was 57.0%, 10.9% and 18.8%, respectively. The mucus adenoma was the most aggressive, and was more aggressive than medium- and poor- differentiation adenoma. The well-differentiated adenoma was not so aggressive as the others. The survival analysis revealed that the differentiation, lymph node metastasis and nerve metastasis remark ably influenced the postoperative survival. Conclusions The differentiation and lymph node metastasis are important factors influencing the prognosis of HCC.
出处
《消化外科》
CSCD
2006年第1期49-51,共3页
Journal of Digestive Surgery
关键词
胆管肿瘤
肝门部胆管癌
预后
bile duct tumor
hilar cholangiocarcinoma
prognosis
