摘要
本文观察了蜂花粉水提取物对无水乙醇与０．６ｍｏｌ／ＬＨＣＩ所致的小鼠胃粘膜还原型谷胱甘肽（ＧＳＨ）和脂质过氧化物（ＬＰＯ）水平变化的影响作用。结果显示：无水乙醇与０．６ｍｏｌ／ＬＨＣｌ灌胃均可引起胃粘膜ＧＳＨ水平下降而ＬＰＯ水平升高，事先用蜂花粉水提取物灌胃对无水乙醇与０．６ｍｏｌ／ＬＨＣｌ所致的胃粘膜ＧＳＨ水平下降和ＬＰＯ水平升高均有显著的抑制作用。提示：胃粘膜ＧＳＨ水平与ＬＰＯ水平呈负相关，蜂花粉水提取物可提高胃粘膜ＧＳＨ水平、降低ＬＰＯ水平。
Abstract Thisexperimentwascarriedouttostudytheeffectofbeepollenwaterextractonthelevelsofreducedglutatbione(GSH)andlipidperoxides(LPO)inthegastricmucosaofmice.TheresultsshowedthatthelevelofGSHwasdecreased.whiletbatofLPOwasincreasedinthegastricmacosaoffastedmdceadministratedeitherabsoluteethanol(AE)or0.6molJLhydmchloricacid(HC1)orally.However,thetendencyofdecreasingoftheGSHlevelandincreasingoftheLPOlevelinthegastricmucosaoffastedmiceadmdnistratedorallyeitherwithAEorwitbHC1wereinhibitedbypretreatznentofbeepol-lenwaterextract.ItwassuggestedthatthelevelsofGSHandLPOinthegastricmucosawasnegativelyrelatedtoeachotherandbeepollenwaterextractcouldincreasetheGSHlevel,decreasetheLPOJevelinthegastricmucosa.MeSHHoneypollen.Glutathione.Lipidperoxides.Gastricmucosa.Aloobol,Ethyl.Hydrochloricacid
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1996年第5期478-481,共4页
Chinese Journal of Pathophysiology
