摘要
受精是一个复杂的生物学过程,精子必须具备良好的运动功能,同时需经获能和顶体反应才能实现受精。通过添加外源性物质,来改善精子体外存活时间,提高精子的运动能力,尤其是冷冻保存精子解冻后的受精能力,被认为是借助实验手段在体外改善精子功能,从而提高受精率的一个有效途径。可添加的外源性生物活性物质种类很多,通常有咖啡因、氨基多糖类物质、己酮可可碱、生殖激素类物质、细胞因子、维生素、抗氧化剂、牛黄酸和一些酶类物质等。本文对精子常用的外源性添加物质的研究进展进行了总结,在此基础提出了寻找新的外源添加物质的思路和途径。
Fertilization is a complex biological process. Motile spermatozoa can fertilize only after they undergo capacitation and acrosomal reaction. Exogenous substances are used to extend sperm survival time, increase sperm, motility ,and improve frozen sperm fertilizing capacity, which is a effective method for improving sperm function under lab condition. At present, various exogenous substances such as caffeine, amido amylose, pentoxifylline, reproductive hormones, cytokines, vitamins, antioxidants, taurine and some enzymes are added to improve fertilization rate. This paper summarizes the advance of exogenous substances that improve sperm fertility and put forward some new ideas and approaches for searching new exogenous substances.
出处
《动物学杂志》
CAS
CSCD
北大核心
2006年第4期122-127,共6页
Chinese Journal of Zoology
基金
中国大熊猫繁育研究基金"提高大熊猫冷冻精子受精能力研究"项目资助(No.2003010)
关键词
受精能力
生物活性物质
冷冻精液
精子
Fertilizing capacity
Bioactivity substance
Frozen semen
Spermatozoa
