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甘糖酯和藻酸双酯钠治疗急性脑梗死临床疗效和实验室的对比研究 被引量:3

CLINICAL AND LABORATORY OBSERVATION ON TREATING ACUTE CEREBRAL INFARCTION WITH PROPYLENE GLUCOL MANNURATE SULFATE(PGMS) AND PSS
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摘要 对甘糖酯(PGMs)和藻酸双酯钠(PSS)治疗急性脑梗死的临床疗效和实验室变化进行了对比研究,发现PGMS治疗急性脑梗死的临床疗效虽优于PSS,但无统计学意义,可能与病例少有关。对患者的血脂、血粘度和凝血指标和变化进行了对比,发现PGMS的降血脂、降血粘度的作用优于PSS,而抗凝血作用则低于PSS。在治疗过程中PGMS无一例出现毒副作用。研究结果表明,PGMS治疗急性脑梗死的临床疗效、实验室变化优于PSS,而且无毒副反应,值得临床推广应用。 We analysed the therapeutic effect and laboratory findings in the patients of a-cute cerebral infarction treated with PGMS and PSS. The results show that the efficient rate of PGMS group was obtained to 95. 6% and 70. l%,and was better than that of PSS group, but there was no statistic significance. The laboratory findings show the i both of them had the effect of anticogau ant and decreasing blood viscosity and serum co tents of lipids. But PGMS had a slight anticoagulant effect and could obviously decrease olood viscosity and serum contents of lipids. here was no side effects in the PGMS group. So PGMS is considered to be a prospective drug for treating acute cerebral infarction.
出处 《中国海洋药物》 CAS CSCD 1996年第2期38-41,共4页 Chinese Journal of Marine Drugs
关键词 脑梗塞 急性脑梗塞 甘糖酯 藻酸双酯钠 药物疗法 Acute cerebral infarction PGMS PSS
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