摘要
本文对新疆奇台及阜康两地大沙鼠与白蛉体内利什曼原虫引起的ＢＡＬＢ／ｃ小鼠及背纹仓鼠组织病变作了观察。结果发现其损害与克拉玛依地区利什曼原虫所致的相似，从而在致病力方面进一步证实了两地原虫均为都兰利什曼原虫的鉴定。在实验条件下，组织病理学的原虫阳性检出率远较涂片的为高。ＢＡＬＢ／ｃ小鼠皮肤血管内原虫的发现，为都兰利什曼原虫全身性转移的途径，提供了组织病理学的依据。
The histopathological changes of BALB/c mouse and Cricetulus barabensis induced by leishma-nia obtained from big gerbilles and sandflies in Qitai and Fukang areas of Xinjiang were investigated. Besidesthe above observations,it was also compared with the before works which were carried out in Karamay area. he results showed that it not only caused the focal tissue inflammatory reaction,tissue degeneration andnecrosis,but might shift to the liver,spleen,lymphnode,kidney and bone-marrow. So the histopathological al-teratiOns were almost the same as the observations in Karamay area. According to the results mentionedabove,this paper further proved that the leishmania separated from big gerbilles and sandflies in Qitai andFukang areas was also the same as the Leishmania turanica seen in Karamay. The results also suggested that,under the laboratory condition,the positive rate of leishmania was markedly high in histopathological investi-gation than that in the smear examination. First discovery of leishmania in blood vessel provided thehistopathological basis for metastasis route of leishmania.
出处
《地方病通报》
1996年第2期19-21,共3页
Endemic Diseases Bulletin
基金
国家自然科学基金
关键词
利什曼原虫
致病力
组织病理学
转移途径
Leishmania turanica
Pathogenicity
Smera examination
Histopathological observation
Metastasis routeThe project was supported by Natural Science Foundation of China
WHO Collaboration Centre for Malaria, Schistosomiasis and Filariasis.
