摘要
蒙古白蛉和安氏白蛉在叮咬了感染当地大沙鼠耳组织内利什曼原虫的BALB/c小鼠后,当白蛉的胃皿仔在时,利什曼前鞭毛体的感染率分别为37.6％和52.9％,在胃血完全消化后,则感染率下降为83％和6.9％,其原因是白蛉吸血后形成的围食膜限制了大多数蛉胃内前鞭毛体的发展;但这二种白蛉在胃血消化过程中约有1/4的围食膜可以破裂,从膜内逸出的前鞭毛体即可继续繁殖和向蛉的消化道前端移行,并且不再受到下一次吸血后形成的围食膜的限制。硕大白蛉吴氏亚种在吸了感染利什曼原虫的小鼠的血后也形成围食膜,但于吸血后第三天膜即破裂,故白蛉感染的前鞭毛体的繁殖和发展不受限制,感染率在蛉胃内有血时为62.8％,无血时为55.6％(P>0.05),无甚差异。
Two species of sandflies Phlebotomus mongolensis and P. andrejevi were fed on BALB / c mice infected with Leishmania from a big gerbil in Karamay (MRHO / CN /88/ KXG-2). After feeding, the promastigote infection rates of the sandflies were found to be 37.6% and 52.9% respectively upon examining the blood in the stomach, which dropped to 8.3% and 6.9% after the blood meal was completely digested. Because after taking the blood meal a peritrophic membrane was developed and enclosed the blood together with the promastigotes in stomach in most sandflies. During the blood meal was being digested, the peritrophic membrane became smaller, but still entirely encircled, eventually it pass into the hingut and was discharged from the anus. However, in about 1 / 4 of the sandflies, the peritrophic membrane was broken in the process of blood disgestion and the promastigotes were free in the stomach and migrated to the proventriculus and esophagus. The peritrophic membrane formed in the next blood meal could not completely envelop these promastigotes. It appears that these sandflies could maintain infection throughout its whole life. In P.major wui the peritrophic membrane was also formed after sucking blood, but in the 3rd day it broke into pieces and the promastigotes development was not limited. The promastigote infection rate was noted to be 62.8% while detecting the blood in the stomach, and 55.6%, when the blood meal completely disappeared from the gut (P>0.05).The promastigotes were able to invade the pharynx and buccal cavity.
出处
《地方病通报》
1992年第2期64-68,共5页
Endemic Diseases Bulletin
基金
国家自然科学基金
关键词
白蛉
利什曼原虫
利什曼病
Sandfly
Big gerbil
Leishmania
Artificial infection
Peritrophic membrane
BALE / c mice
