摘要
目的:评价胃癌患者的生活质量并分析其影响因素,以期为改善胃癌患者的生活质量提出改进措施。方法:于2003-06-01/12-31在山东大学随机抽取3家医院,选择入院治疗的147名胃癌患者为调查对象。患者本人了解病情,预期生存时间在1个月以上,自愿参加调查。采取面访的形式进行调查,内容包括一般状况调查表、生活质量核心问卷(共30个条目,包括5个功能尺度、3个症状尺度、6个单项测量项目和1个整体生活质量评价尺度。每个尺度的原始得分均通过线性化转换为0～100分,分数越高说明患者的总体生活质量越好)及胃癌患者生活质量问卷(共包括5个测量尺度和4个单项测量项目,每个尺度的得分通过线性化转换为0～100分,症状及副作用尺度得分越高表明病情越严重)。采用协方差分析、多重线性回归分析等方法进行资料分析。结果:得到合格问卷140份,应答率为95.2%。①患者生活质量总评分为40.95±16.63。②生活质量总评分与年龄呈负相关(r=-0.334P<0.01);外向型、中间型、内向型性格与生活质量总评分做等级相关分析,等级相关系数为-0.251(P<0.01)。③疼痛、吞咽困难饮食受限3个症状尺度进入以生活质量总评为应变量的多重回归方程(F=34.109,P<0.01)。结论:胃癌患者的总体生活质量较差,其中年龄、性格类型以及疼痛、吞咽困难、饮食受限等症状对生活质量有明显影响,在治疗中应区别对待。
AIM： To evaluate the quality of life （QOL） and the main influencing factors in patients suffering from gastric cancer, so as to provide measures for improving their QOL.
METHODS： From June 1^st to December 31^st in 2003, 147 patients with gastric cancer were randomly selected from three hospitals in Jinan city as the subjects. The patients all knew their own conditions of disease, the expected survival was above 1 month, and they all voluntarily participated in the study. The patients were investigated by means of face-toface interview, the contents included the general status inventory, QOL core questionnaire and QOL questionnaire for patients with gastric cancer. The QOL core questionnaire consisted of 30 items, including 5 scales for the function, 3 scales for the symptoms, 6 single measurement item and 1 scale for the evaluation of general QOL; the original score for each scale was transformed to 0-100 points with linearization; the higher the score, the better the general QOL of the patients. The QOL questionnaire for patients with gastric cancer had 5 measurement scales and 4 single measurement items, the score for each scale was transformed to 0-100 points with linearization, the higher the scores of the scales for symptoms and side effects, the more severe the disease. The data were analyzed with the analysis of covariance, multivariate linear stepwise regression.
RESULTS： Totally 140 qualified questionnaires were obtained, and the rate for response was 95.2%. ① The total score of QOL in the patients was 40.95±16.63, ② The total score of QOL was negatively correlated with age （r=-0.334, P 〈 0.01）. The rank corrdation coefficient of extraversion, medium and introversion was -0.251 （P 〈 0.01）. ③ The scales of the symptoms of pain, dysphagia and dietary restriction entered multivariate regression equation taking the total score of QOL as the dependent variable （F=34.109, P 〈 0.01）.
CONCLUSION： The QOL of patients with gastric cancer is poorer, and the factors of age and type of character, and the symptoms of pain, dysphagia and dietary restriction have obviously influence on the QOL, and should be differently treated in the treatment.
出处
《中国临床康复》
CSCD
北大核心
2006年第18期20-22,共3页
Chinese Journal of Clinical Rehabilitation
