摘要
【目的】研究腹部超声引导下胚胎移植对体外受精-胚胎移植结局的影响。【方法】回顾性分析2001年7月至2005年3月,在本中心接受体外受精-胚胎移植(包括卵母细胞内单精子注射)治疗的461名患者521个周期的资料,按照胚胎移植时有无B超引导分为常规胚胎移植组(A组)和超声引导下胚胎移植组(B组),分别有187个周期和334个周期,比较两组患者的临床妊娠率、胚胎种植率、胚胎残留率和异位妊娠率。【结果】A组和B组的周期妊娠率分别是35.8%(67/187)和38.3%(128/334),P>0.05;胚胎种植率分别是17.4%(104/599)和23.2%(179/773),P<0.01;胚胎残留率分别是3.7%(7/187)和0.3%(1/334),P<0.01;异位妊娠率分别是3.0%(2/67)和1.6%(2/128),P>0.05。【结论】腹部超声引导下胚胎移植能提高体外受精-胚胎移植的胚胎种植率,降低胚胎残留率,可能有助于改善临床妊娠率和降低异位妊娠率,是一种有效的胚胎移植方法。
[Objective] To investigate the effect of transabdominal ultrasound-guided embryo transfer on the outcome of in vitro fertilization-embryo transfer （IVF-ET）. [Methods] The data of 461 patients undergoing IVF-ET （including intracytoplasmic sperm injection） therapy for 521 cycles in our Reproductive Medicine Center were analyzed retrospectively. The patients were divided into two groups： the traditional group （group A） and the ultrasound-guided group （group B）, including 187 cycles and 334 cycles, respectively. The clinical pregnancy rate, implantation rate, embryo retention rate, and ectopic pregnancy rate between two groups were compared. [Results] The clinical pregnancy rates of group A and group B were 35.8% （67/187） and 38.3% （128/334）, P 〉0.05; the implantation rates were 17.4% （104/599） and 23.2% （179/773）, P〈 0.01; the embryo retention rates were 3.7% （7/ 187） and0.3% （1/334）, P〈0.01; the ectopic pregnancy rates were 3.0% （2/67） and 1.6%（2/128）, P〉0.05. [Conclusion]Transabdominal ultrasound-guided ET can increase the implantation rate and decrease the embryo retention rate, may be helpful to improve the clinical pregnancy rate and decrease the ectopic pregnancy rate, so it is an effective technique for embryo transfer.
出处
《中山大学学报（医学科学版）》
CAS
CSCD
北大核心
2006年第2期208-211,共4页
Journal of Sun Yat-Sen University:Medical Sciences
基金
广东省卫生厅科研基金资助项目(A2003216)
关键词
超声引导
体外受精
胚胎移植
妊娠率
ultrasound guided, in vitro fertilization, embryo transfer, pregnancy
