摘要
线粒体DNA(Mitochondrial DNA,mtDNA)是线粒体内具有遗传效应的双股闭环DNA分子,其遗传信息量虽小,却控制着线粒体一些最基本的性质,对细胞及其功能有着重要影响。mtDNA的损伤会导致细胞结构及功能的变化,已越来越引起人们的重视。本文就近年来mtDNA的损伤及其对细胞影响的研究进展作一综述。
Mitochondrial DNA（mtDNA）, a double-stranded circular molecular, encodes several genes essential for mitochondrial and cellular functions despite its small amount of genetic information. Damage of mtDNA can lead to changes of cellular structures and functions and this fact is drawing more and more attention. This review summarized the recent research about mtDNA damage and its influence on cells.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2006年第2期211-214,共4页
Academic Journal of Second Military Medical University
