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VEGF-C和CD34在涎腺腺样囊性癌中的表达 被引量：2

Expression of vascular endothelial growth factor-C and CD34 in adenoid cystic carcinoma of salivary glands
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摘要 目的研究VEGF-C和CD34在涎腺腺样囊性癌(SACC)中表达及其与临床病理的关系,探讨ACC转移机理。方法采用免疫组化SP法,检测42例ACC中VEGF-C和CD34表达情况,并计算微血管密度(MVD),采用SPSS软件行统计学分析。结果VEGF-C的表达和MVD与ACC组织类型有关(P=0.000;P=0.001);MVD和VEGF-C表达间无相关性(P=0.165)。结论VEGF-C和MVD可作为ACC分化的指标之一;VEGF-C可能与ACC淋巴结转移有关。 Objective To investigated the expression of VEGF-C and CD34 and to understand the metastatic mechanism of adenoid cystic carcinoma （ACC） of salivary glands. Methods Immunohistochemical staining （SP） was used to determine the expression of VEGF-C and CD34 in 42 cases of ACE3 of salivary gland and to quantify the MVD. SPSS statistical software was used in this study. Results The expression of VEGF-C and MVD were correlated with the histological pattern （ P=0. 000 ; P=0. 001）. There was no correlation between the expression of VEGF-C and MVD （ P = 0. 165 ）. Conclusion In the ACC, VEGF-C expression and MVD might be used as predictors for the differentiation. VEGF-C may be correlated with the lymph node metastasis.
作者 汤晓飞 吴洪儒 汪育苗 王凤光 刘晓勇
机构地区 首都医科大学附属北京口腔医院病理科
出处 《现代口腔医学杂志》 CAS CSCD 北大核心 2006年第1期41-44,共4页 Journal of Modern Stomatology
关键词 VEGF-C 微血管密度 涎腺 腺样囊性癌 转移 VEGF-C MVD Adenoid cystic carcinoma Salivary glands Metastasis
分类号 R739.8 [医药卫生—肿瘤]
  • 相关文献

参考文献12

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共引文献45

同被引文献17

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现代口腔医学杂志
2006年 第1期

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