摘要
[目的]探讨高胆红素血症婴幼儿的听力学特征，为临床诊治提供理论依据。【方法】对54例（108耳）高胆红素血症患儿进行听觉脑千诱发电位（auditory brainstem response，ABR）及畸变产物耳声发射（distortion product otoacoustic emissions．DPOAE）测试，设立同年龄段正常对照组、蜗性病变对照组、中枢神经系统病变组进行对比研究。【结果】高胆组本身，可出现双耳蜗性、双耳蜗后、双耳ABR及DPOAE严重异常、双耳中一耳为蜗性、一耳为蜗后的不同表现；与中枢组比较。高胆组表现为蜗后病变的比率较中枢组高（P〈0．05）；与正常组相比，除F7外，高胆组各频点的DPOAE幅值均较低；F6～F11各频点的引出率与正常组相比无明显差异；与蜗性病变组相比，高胆组的波V阈值较高（P〈0．05）；与蜗性病变组及正常组相比，高胆组的Ⅰ、Ⅲ、Ⅴ波潜伏期均延长（P〈0．05）。【结论】高胆红素血症婴幼儿在听力测试中可表现多种多样的特征。
[Objective] To explore the audiological characteristics in infants with hypercholesterolemia. [Methods] 54 infants（ 108 ears） with hypercholesterolemia were tested by auditory brainstem response（ABR） and distortion product otoacoustic emissions（DPOAE）. Some same age healthy infants（control groupl ） with cochlear lesion（control group2） and infants with CNS diseases（control group3） were included. [Results] In the study group, the audiological results manifested cochlear lesion, retrocochlear lesion,the severe abnormal results of ABR and PDPOAE and cochlear lesion in one ear while retrocochlear lesion in the other. The occurrence rate of retrocochlear lesion in the study group was higher than that in the control group 3. Except F7, when compared with control group 1, the DPOAE amplitudes at all frequencies were lower. The occurrence rate at F6-F11 Was the same as that in the control group 1. The threshold of wave V was higher than it in the control group 2. The latency values of waves Ⅰ , Ⅲ and Ⅴ were prolonged when compared with control group 1 and control group 2. [Conclusion] The audiological characteristics in infants with hypercholesterolemia is varied.
出处
《中国儿童保健杂志》
CAS
2006年第1期35-37,共3页
Chinese Journal of Child Health Care
关键词
高胆红素血症
脑干听觉诱发电位
畸变产物耳声发射
婴幼儿
hypercholesterolemia
auditory brainstem response
distortion product acoustic emission
infants
