摘要
目的研究高胆红素患儿听力障碍的发生率,探讨与听力障碍发生有关的高危因素。方法采用畸变产物耳声发射(DPOAE)对高胆红素血症患儿于病情稳定、出院前行听力筛查初筛,未通过者于生后42 d左右进行复筛,复筛未通过者行听觉脑干反应(ABR)确诊检查;选取产科出生正常新生儿作为对照。结果检测高胆红素血症患儿235例,初筛异常58例,占24.7%;复筛58例,异常11例,占18.9%;复筛未通过者3个月龄时行ABR检查,确诊听力障碍5例,高胆红素血症患儿听力障碍发生率为2.13%(5/235)。检测对照组正常新生儿182例,初筛异常18例,占9.9%;18例复筛均通过。结论高胆红素血症患儿是听力障碍发生高危人群。先天性巨细胞病毒感染、新生儿败血症及溶血病是导致发生听力障碍的危险因素。对高危新生儿应进行听力随访。
Objective To investigate the incidence of heating disorder and analyse the high risk factors with hearing injury in newborns with hyperbilirubinemia. Methods The newborns with hyperbilirubinemia who admitted to the department of neonate, were received the distortion product otoacoustic emission （DPOAE）test when they recovered from hyperbilirubinemia; those babies who didn＇t pass the first test received screening again in 42 days after birth. Those babies who didn＇t pass the second test received auditory brain stem response（ABR）test. Results Fifty- eight（33.2%）newborns didn＇t pass the first DPOAE test among 235 newborns with hyperbilirubinemia; 11 （ 18.9 % ） infants didn＇t pass the second DPOAE test among 58 infants; 5 infants failed to pass the ABR test, the ratio of hearing disorder in newborns with hyperbilirubinemia was 2.13% ; 18（9.9% ）newborns didn＇t pass the first DPOAE test among 182 normal newborns, and those infants all passed the second DPOAE test. Conclusions Hyperbilirubinemia is high - risk population of hearing disorder. The congenital cytomegalovirus infection, neonatal septicemia and hemolytic disease of newborn are the high risk factors responsible for hearing disorder. All high risk newborns should recieve hearing examination regularly.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2006年第17期1164-1165,共2页
Journal of Applied Clinical Pediatrics
基金
湖南省计划生育委员会项目资助(2002-13)
关键词
听力障碍
听力检查
高胆红素血症
婴儿
新生
hearing disorder
hearing examine
hyperbilirubinemia
infant, newborn
