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血液透析患者甲状旁腺素和血小板胞内游离钙变化及相互关系 被引量:3

Changesandtheircorrelationofparathyroidhormoneandplateletcytosolicfreecalciumonhemodialysispatients
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摘要 了解血透患者血清全段甲状旁腺素[PTH(1~84)]与血小板胞内游离钙浓度{pt[Ca2+]i}的变化及其互相关系。方法用Fura-2荧光测定法和免疫放射法对24例血透患者测定上述两项内容。结果HD患者的静息pt[Ca2+]i;和PTH(1~84)是升高的,透析后则降低。静息pt[Ca2+]i与PTH(1~84)相关,其P值透前为<0.001,透后为<0.05。结论PTH(1~84)是主要影响pt[Ca2+]i水平的因素。 bjectiveToobservethechangesandtheircorrelationofparathyroidhormone[PTH(1~84)]andplateletcytosolicfreecalcium{pt[Ca2+]i}onhemodialysis(HD)patients.MethodsFura-2fluorometryandimmunora-dioassaywereusedtodetectPTH(1~84)andpt[Ca2+]iin24HDpatients.ResultsTherestingpt[Ca2+]iandPTH(1~84)increasedinHDcasesanddecreasedafterhemodialysis.Therestingpt[Ca2+]iwascorrelatedtoPTH(1~84),itsPvaluewas<0.001beforeHDand<0.05afterHD.ConclusionPTH(1~84)isamainfactoraf-fectingthelevelofpt[Ca2+]i.
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 1996年第5期269-272,共4页 Chinese Journal of Nephrology
关键词 甲状旁腺素 血小板胞内 游离钙 血液透析 尿毒症 ParathyroidhormonePlateletcytosolicfreecalciumHemodialysisFura-2fluorometryIm-munoradioassay
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同被引文献18

  • 1李建华,孙继领,高小环,王京庆.应用Fura-2/Am检测血小板胞浆游离钙浓度[J].中华血液学杂志,1996,17(9):493-494. 被引量:4
  • 2章俊,曾熙兰,李向阳,李希杰,徐钟源.血液透析对尿毒症患者全段甲状旁腺素的影响[J].标记免疫分析与临床,1996,3(1):15-16. 被引量:2
  • 3丛涛,赵霖.检测红细胞胞浆内钙离子浓度的Fura-2荧光光度法[J].国外医学(临床生物化学与检验学分册),1996,17(1):32-34. 被引量:2
  • 4Yudd M,Llach F. Renal Osteodystrophy. In:Owen WF,Pereim BJG and Sayegh MH, Dialysis and Transplantation, 1 st edition, W. B. Saunders,2000.253-279.
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  • 7Fernandez E ,IJach F. Guidelines for dosing intravenous calcitriol in dialysis patients with hyperphosphatemia. Nephrol Dial Transplant, 1996,11(suppl 3 ) :s96-s101.
  • 8Reichel H,Szabo A,Uhl J,et al. Intermittent versus continuous administration of 1,25 (OH)2D3 in experimental renal hyperparathyroidism.Kidney Int, 1993,44 : 1259-1265.
  • 9Ramirez JA, Emmentt M, White MG, et al. The absorption of dietary phosphorus and calcium in haemodialysis patients. Kidney Int, 1986,30:753-759.
  • 10陈晓春,刘楠,张洪,郑安.小剂量阿司匹林对老年脑梗塞患者血小板胞浆游离钙浓度的影响[J].中华老年医学杂志,1997,16(3):147-149. 被引量:5

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