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条件性噪声对噪声性耳聋保护作用 被引量：1

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摘要 条件性噪声(soundconditoning)的保护现象是指预先给动物低水平的长期的声音刺激可以对抗由高强度噪声引起的永久性阈移,已证实大多哺乳动物普遍存在该现象。研究多集中于内耳的形态、生理的变化,也有代谢活性、中耳肌反射、热休克蛋白等因素可能参与保护作用,但其确切的机制还不是十分清楚。本文从刺激声音频率、刺激时间等方面对条件性噪声的特点进行总结,同时探讨可能机理。
作者 谢华顺 宋为明
机构地区 北京大学第三医院耳鼻咽喉科
出处 《国外医学（耳鼻咽喉科学分册）》 2005年第6期356-358,共3页 Foreign Medical Sciences(Section of Otolray Ngology Foreign Medical)
关键词 噪声(Noise) 聋(Deafness) 听觉(Auditory Perception) 噪声性耳聋 保护作用 条件性 哺乳动物 热休克蛋白 声音刺激 代谢活性 声音频率
分类号 R764.433 [医药卫生—耳鼻咽喉科] R151.1 [医药卫生—营养与食品卫生学]
  • 相关文献

参考文献18

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二级参考文献11

  • 1Henry KR,Chole RA.Hypothermia protects the cochlea from noise damage[].Hearing Research.1984
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  • 10Henderson D,Campo P.Development of resistance to noise[].In: Noise-Induced Hearing Loss.1992

共引文献19

同被引文献33

  • 1吴铭权.噪声习服的研究[J].国外医学（卫生学分册）,1995,22(2):69-72. 被引量：14
  • 2曹华,董明敏,赵春红,李宏慧.条件声暴露后豚鼠耳蜗外毛细胞丝束肌动蛋白表达的改变[J].临床耳鼻咽喉科杂志,2006,20(22):1035-1037. 被引量：5
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  • 4Subramaniam M, Henderson D, Spongr VP. Protection from noise induced hearing loss: is prolonged 'conditioning" necessa- ry[J]. Hear Res,1993,65: 234.
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  • 6Dallos P, Wu X, Cheatham MA, et al. Pre;tin--based outer hair cell motility is necessary formammalian ~ochiear amplifi- cation[J]. Neuron,2008,58: 333.
  • 7Zuo H, Cui B, She X, et al. Changes in guinea pig cochlear hair cells after sound conditioning and noise exposure[J]. J Occup Health,2008,50: 373.
  • 8Cody AR,Johnstone BM. Temporary threshold shift modified by binaural acoustic stimulation[J]. Hear Res, 1982,6:199.
  • 9Pukkila M, Zhai S, Virkkala J, et al. The "toughening" phe- nomenon in rat's auditory organ[J]. Acta Otolaryngol Suppl, 1997,529: 59.
  • 10Niu X, Bogdanovic N, Canlon B. The distribution and the modulation of tyrosine hydroxylase immunoreactlvlty in the lateral olivocochlear system of the guinea--pig[J], Neuro- science, 2004,125 : 725.

引证文献1

二级引证文献3

国外医学（耳鼻咽喉科学分册）
2005年 第6期

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