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老年性聋的基因组学研究进展 被引量：12

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摘要 老年性聋是老年人群中最常见的健康问题之一,老年性聋可能既是生理性的衰老现象,又是一种与遗传及生命过程中所遭受到的各种有害因素影响有关的病理现象。本文将近年来在老年性聋基因组学研究进展情况作一综述。
作者 关静 郭玉芬 王秋菊
机构地区 甘肃省兰州大学第二医院耳鼻咽喉头颈外科 中国人民解放军总医院耳鼻咽喉头颈外科
出处 《国际耳鼻咽喉头颈外科杂志》 2006年第1期56-59,共4页 International Journal of Otolaryngology-Head and Neck Surgery
基金 国家自然科学基金面上项目(30370782及30470956) 北京市重大科技项目(H020220020610) 高等学校全国优秀博士学位论文作者专项资金资助项目(200463)
关键词 聋(Deafness) 基因组(Cenome)
分类号 R764.436 [医药卫生—耳鼻咽喉科]
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参考文献20

  • 1Zhu M,Yang T,Wei S,et al.Mutations in the γ-actin gene(ACTG1)are associated with dominant progressive deafness(DFNA20/26).Am J Hum Genet,2003,73(5):1082-1091.
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  • 3Nemoto M,Morita Y,Mishima Y,et al.Ahl3,a third locus on mouse chromosome 17 affecting age-related heating loss.Biochemical and Biophysical Research Communications,2004,324(4):1283-1288.
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  • 8Zheng QY,Johnson KR.Hearing loss associated with the modifier of deaf waddle(mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice.Hear Res,2001,15 4(1-2):45-53.
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二级参考文献13

  • 1方克明,钟国民,占木水,龚文亮,万静.测土配方施肥在晚稻上的应用效果初探[J].江西农业学报,2010,22(8):75-77. 被引量：15
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  • 10Johnson KR, Gagnon LH, Webb LS, et al. Mouse models of USH1C and DFNB18: phenotypic and molecular analyses of two new spontaneous mutations of the Ush1c gene [J]. Human Molecular Genetics, 2003,12(23):3075-3086.

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国际耳鼻咽喉头颈外科杂志
2006年 第1期

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