摘要
目的:探讨儿童重度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的听性脑干反应(ABR)的特征。方法:对37例(74耳)重度OSAHS儿童(OSAHS组)进行ABR测试,并与20例(40耳)正常儿童(对照组)进行比较。结果:①OSAHS组患儿ABRⅠ、Ⅲ、Ⅴ波的潜伏期分别为(1.67±0.20)ms,(3.87±0.31)ms,(5.70±0.31)ms;对照组分别为(1.60±0.11)ms,(3.81±0.23)ms,(5.61±0.23)ms;2组比较,ABRⅠ波潜伏期的延长有统计学意义(P<0.05)。②OSAHS组Ⅰ～Ⅲ、Ⅲ～Ⅴ、Ⅰ～Ⅴ波间期分别为(2.19±0.19)ms,(1.82±0.22)ms,(4.01±0.22)ms;对照组分别为(2.26±0.15)ms,(1.73±0.21)ms,(4.05±0.23)ms;2组比较,Ⅲ～Ⅴ波间期的延长及Ⅰ～Ⅲ波间期的缩短有统计学意义(P<0.05)。③与对照组相比,OSAHS组波Ⅴ反应阈的提高有统计学意义(P<0.05)。结论:重度OSAHS患儿的ABR测试结果异常,提示OSAHS对耳蜗及听觉脑干的功能都存在影响。
Objective：To explore the characteristics of auditory brainstem response（ABR） in severe obstructive sleep apnea-hypopnea syndrome. Method： ABR was recorded in 37 severe OSAHS patients （OSAHS group） and 20 controls. Result：①In the OSAHS group,the latency values of waves Ⅰ , Ⅲ andV were （1.67±0.20）ms, （3.87 ± 0.31 ） ms, （5.70± 0.31 ） ms respectively . In the control group, the latency values of waves Ⅰ , Ⅲ and Ⅴ were （ 1.60 ± 0.11 ） ms, （3.81 ± 0.23 ） ms, （5.61±0. 23 ） ms respectively. A statistically significant prolongation was found in the latency values of waves Ⅰ in OSAHS group compared to control group（ P 〈0. 05）. ②When comparing to the control group, the transmission time between waves Ⅲ and Ⅴ was found to be prolonged and waves Ⅰ and Ⅲ to be shortened in the OSAHS group. Furthermore, the change was considered statistically significant（ P 〈0.05）.③A statistically significant elevation was found in response threshold of wave Ⅴ when comparing to the control group（ P 〈0.05）. Conclusion： The pathological sleepiness seen in OSAHS patients may cause ABR abnormalities, as a consequence of the chronic hypoxic and hypercapnic status occurring in the brain-stem and cochlear.
出处
《临床耳鼻咽喉科杂志》
CSCD
北大核心
2005年第19期868-870,共3页
Journal of Clinical Otorhinolaryngology
