摘要
以３－氯４－氟苯胺为起始原料，经六步反应合成盐酸环丙沙星，总收率达４２．３％，高于现有文献报道值。经元素分析、红外光谱和核磁共振谱确认了产物的结构。
Ciprofloxacin hydrochloride monohydrate was synthesized from 3-chloro-4-fluoaniline by six-step process.The overall yield could be up to 42. 4%.The structure of products was identified by elementary analysis, infrared spectroscopy and nuclear magnetic spectrum.
出处
《化学研究与应用》
CAS
CSCD
1996年第2期292-294,共3页
Chemical Research and Application
关键词
盐酸环丙沙星
合成
3-氯-4-氟苯胺
Ciprofloxacin hydrochloride monohydrate,Synthesis,3-Chloro-4-fluoraniline
