摘要
目的:探讨颈椎管狭窄症患者黄韧带肥厚的组织学变化及其临床意义。方法:对68例颈椎管狭窄症患者肥厚的黄韧带进行组织学及免疫组化染色研究。结果:58例(85.3%)肥厚的黄韧带内有血管增生及大量炎细胞浸润;其免疫组化染色KP-1均为阳性,49例LCA染色阳性。10例(14.7%)肥厚的黄韧带组织内未见炎细胞浸润,其免疫组化染色KP-1及LCA染色均阴性。11例(16.2%)肥厚黄韧带中发现了钙化或骨化灶。本组9例术前影像学显示不稳定节段的肥厚黄韧带内均发现了炎症反应。结论:颈椎管狭窄症患者黄韧带肥厚的原因之一可能是组织中出现了慢性炎症反应;颈椎不稳定可能是造成黄韧带内炎症反应的原因之一。
Objective：To evaluate the clinical meaning of ligamentum flavum hypertrophy in the patients with cervical spinal canal stenosis.Method：Ligamentum flavum from 68 patients with cervical spinal canal stenosis were used for histologic and immunohistochemical examination.Result：58 patients（85.3%） showed abundant inflammatory cell infiltration in their ligamentum flavum.The immunuhistochemical examination of the 58 patients showed that.all of them had positive results of KP-1 and 49 had positive results of LCA,10 patients （14.7%） had no inflammatory cell infiltration.and their immunohistoehemical results were all negative.Calcified or ossificatory ligamentum flavum were found in 11 patients （16.2%）,9 cases with cervical instability were all found inflammation in their ligamentum flavum at the instable segment.Conclusion：There is chronic inflammatory reaction in the ligamentum flavum of patients with cervical spinal canal stenosis,and it is a cause of ligamentum flavum hypertrophy,It is found cervical istability may be a cause of inflammation in ligamentum flavum.
出处
《中国脊柱脊髓杂志》
CAS
CSCD
2005年第8期483-485,i0002,共4页
Chinese Journal of Spine and Spinal Cord
关键词
颈椎管狭窄症
黄韧带
炎症反应
Cervical spinal canal stenosis
Ligamentum flavum
Inflammation
