摘要
目的探讨CD55,CD59,CD34抗原表达对全血细胞减少症的诊断意义。方法应用流式细胞仪测定全血细胞减少症及对照组粒细胞上CD55,CD59,CD34抗原表达率,并同时做相关血液学试验。结果阵发性血红蛋白尿(PNH),再生障碍性贫血(AA),再障-阵发性血红蛋白尿综合征(AA-PNH)病人CD55,CD59,CD34抗原表达率与正常对照组,相互间有显著差异(P<0.01,P<0.05)。结论粒细胞上CD55,CD59,CD34抗原表达率可作为PNH,AA,AA-PNH综合征诊断指标,具有灵敏性强,特异性高等优点。
Objective To study CD55, CD59 , CD34 in the application of diagnosing hemopenia and differentiation from other diseases ,Methods Antigen expression of CD55, CD59, CD34 on granulocyte of hemopenia patients and normal control were detected by flow cytometry. Simultaneously other haematological tests were done and their correlation were found by statistic treatment . Resuits Antigen expression of CD55, CD59, CD34 on granulocyte of hemopenia patients and normal control were detected by flow cytometry. Simultaneously other haematological tests were done and their correlation were found by statistic treatment . Conclusion CD55, CD59 , CD34of PNH, AA, AA - PNH patients increased evidently than normal people. （ P 〈 0.01, P 〈 0.05 ）. Conclusion Antigen expression of CD55 ,CD59 , CD34on granulocyte may act as indicators of early diagnosing and differentiating hemopenia. They are specially sensitive and particular for diagnosing PNH, AA, AA-PNH.
出处
《临床军医杂志》
CAS
2005年第4期398-399,共2页
Clinical Journal of Medical Officers
