摘要
通过对１６例（男７例，女９例）血清ＨＣＶＲＮＡ阳性的输血后丙型肝炎患者唾液、精液、阴道分泌物的ＨＣＶＲＮＡ检测及其配偶和子女的ＨＣＶ感染状况的调查，表明丙型肝炎患者唾液、精液、阴道分泌物中ＨＣＶＲＮＡ均有较高的检出率，以精液最高（５７．１％，４／７），唾液次之（３１．２％，５／１６），阴道分泌物最低（２２．２２％，２／９）。家庭成员中，２例（１２．５０％）配偶感染ＨＣＶ，１６个家庭的子女无一例感染ＨＣＶ。２例引起家庭内传播者均为慢性丙型肝炎患者。结果显示：通过性接触和日常生活接触均有引起丙型肝炎传播的潜在危险性，其中以性接触传播的危险性较大。病程越长，家庭内传播的可能性越大。因此，对ＨＣＶＲＮＡ阳性患者应进行抗病毒治疗，家庭内应进行适当隔离。
o
investigate the transmission of HCV i nfection through household
contact, we detected HCV RNA in saliva,seminal fluids or vaginal
discharges of l6 serum HCV RNA positive patients(7 men and 9women)
and in sera of their family members,The positive rates of HCV RNA in
saliva seminal fluids or vaginal discharges were
31.25%(5/16),57.14%(4/7)and 22. 22%(2/9) respectively. Among the
family members in our study all descendants were negative for both
anti.HCV and HCV RNA, despite two spouses positive for HCV RNA。 This
result strongly suggested the potential possibility of sexual
transmission of HCV infection. Therefore, all HCV RNA positive
patients should be treated with antivi- ral drugs and isolated in
their families.
基金
国家八.五科技攻关资助课题
