摘要
采用单克隆抗体酶联免疫吸附试验,对5例2～8(10/12)岁反复呼吸道感染患儿的血清免疫球蛋白(Ig)G亚类作了测定,21例同龄健康儿童作为对照组。结果发现IgG_1缺乏症2例;IgG_2-G_4/IgG_2缺乏症2例;另1例血清总IgG、IgM和IgA均下降,IgG亚类呈比例降低,诊断为常见变异型免疫缺陷病(CVID)。
Immunoglobulin (Ig) G subclasses were measured in serum from 5 children aged 2～8 10/12 yr. with recurrent respiratory tract infections by using monoclonal antibody enzyme-linked immunosorbent assay. 21 age-matched healthy children were studied as the control. IgGl deficiency(2), IgG2/IgG2-G4 deficiency(2) were determined. Another case in whom the total serum IgG, IgM and IgA were very low companied all of IgG subclasses decreased was diagnosed as common variable immunodeficiency (CVI).
出处
《上海免疫学杂志》
CSCD
北大核心
1989年第1期23-26,共4页
Shanghai Journal of Immunology
基金
国家自然科学基金 3870769
四川省卫生科研课题基金 1988资助
