摘要
报告同一家族6例心脏全传导系统缺陷病。连续三代的家系调查显示:符合常染色体显性遗传特征。我们对临床症状比较明显的3例试用腺苷受体桔抗剂(氨茶碱)治疗,疗效显著。结合文献对家族性心脏全传导系统缺陷病的病因进行了探讨,认为可能与家族性腺苷或腺苷酸的代谢异常有关。
Six cases of completeconduction defect in one family were described. An examination of 3 successive generations revealed autosomal dominent hereditary featuers. Adenosine receptor antagonist (Aminophylline) was used for trial to treat three cases with obvious symptoms and resulted in prominent effect. With a review of literature, discussions on the etiology of familial conduction defect of the heart were carried out. It is suggested that familial abnormality in metabolism of adenosine and adenylic acid might be responsible for the occurrence of the disease.
出处
《现代诊断与治疗》
CAS
1993年第3期246-249,共4页
Modern Diagnosis and Treatment
关键词
家族性
心脏传导系统
缺陷病
Familliar Conduction defect Autosomal dominant trait Adenosine receptor antagonist
