摘要
目的 观察小剂量静脉注射丙球 (IVIG)对小儿肺炎、急性腹泻病和反复呼吸道感染等感染性疾病的疗效。方法 观察组予IVIG ,2 0 0～ 30 0mg/ (kg·d) ,1～ 2天 ,其余治疗与对照组相同。比较观察组与对照组的病程长短及某些临床表现的缓解率。结果 用IVIG的肺炎、急性腹泻病和反复呼吸道感染观察组的病程分别为 (7.85± 2 .15 )天、(7.6 0± 2 .17)天、(4 .0 6± 1.4 8)天 ,而未用IVIG的相应的对照组的病程分别为 (9.4 0± 1.90 )天、(8.6 6± 2 .72 )天、(6 .0 5± 1.31)天 ,肺炎和反复呼吸道感染观察组的病程较对照组明显缩短 (Р <0 .0 1、Р <0 .0 1) ;肺炎观察组在病程第 7天 ,发热、肺部罗音的缓解率明显高于对照组 (Р<0 .0 5 ,Р<0 .0 5 ) ;急性腹泻病观察组在病程第 7天 ,大便次数缓解率明显高于对照组 (Р <0 .0 5 ) ;反复呼吸道感染观察组在病程第 4天 ,发热症状缓解率明显高于对照组 (Р <0 .0 5 )。
Objective To observe the curative effect of small dosage IVIG for infectious diseases of children. Methods Observed groups were treated for 1～2 days with IVIG.200～300mg/kg/d. Other treatment for observed groups was as same as control groups. Comparing observed groups to control groups on course of disease, remission rate of some clinical situation. Results After treatment with IVIG, course of pneumonia, acute diarrhea and repeat respiratory tract infection in observed groups was separately (7.85±2.15)days、(7.60±2.17)days、(4.06±1.48)days, and in control groups course of these diseases was separately (9.40±1.90)days、(8.66±2.72)days、(6.05±1.31)days. Course of pneumonia and repeat respiratory tract infection in observed groups was shorter significantly than that in control groups(Р<0.01、Р<0.01).At the seventh day after starting of pneumonia, remission rates of fever and lung rates in observed group were higher significantly than those in control group(Р<0.05,Р<0.05). At the seventh day after starting of acute diarrhea, remission rate of stool times in observed group was higher significantly than that in control group(Р<0.05). At the fourth day after starting of repeat respiratory tract infection, remission rate of fever in observed group was higher significantly than that in control group(Р<0.05). Conclusions The way that conventional therapy combined with small dosage IVIG is benefit to improve infectious diseases of children in advance.
出处
《齐齐哈尔医学院学报》
2004年第5期491-492,共2页
Journal of Qiqihar Medical University
