6Hailer D, Holt L, Kim SC, et al. Transforming growth factor - beta 1 inhibits non -pathogenic Gram negative bacteria - induced NF - kappa B recruitment to the interleukin -6 gene promoter in intestinal ep-ithelial cells through modulation of histone acetylation. J Biol Chem, 2003, 278:23851 - 23860.
7Suarez Cuervo C, Harris KW, Kallman L,et al. Tumor necrosis factor - alpha induees interleukin -6 production via extracellular-regulated kinase 1 activation in breast cancer cells. Breast Cancer Res Treat,2003, 80:71 -78.
8Park JI, Lee MG, Cho K, et al. Transforming growth factor - betal activates interleukin- 6 expression in prostate cancer cells through the synergistic collaboration of the Smad2, p38 - NF - kappaB, JNK, andRas signaling pathways. Oncogene, 2003,22:4314 - 4332.
10Verrecchia F, Mauviel A. Transforming growth factor - beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation. J Invest Dermatol, 2002, 118:211 -215.
8[1]Singh J,Ling LE,Sawyer JS,et al.Transforming the TGF-β path way:convergence of distinct lead generation strategies on a novel ldnase pharmacophore for TβR I (ALKS)[J].Curr Opin Drug Discov Devel,2004,7:437-445.
9[2]Lasky JA,Ortiz LA.Antifibrotic therapy for the treatment of pulmonary fibrosis[J].Am J Med Sci,2001,322:213-222.
10[3]Yu Q,Stamenkovic L Cell surface -localized matrix metalloproteinase-9 proteolytically activates TGF-beta and pro-motes truant invasion and angingenesis[J].Genes Dev,2000,14:163-176.
