期刊文献+

阿托伐他汀治疗不稳定型心绞痛40例疗效分析 被引量:2

暂未订购
导出
摘要 目的 探讨阿托伐他汀治疗不稳定型心绞痛的临床疗效。方法 将 80例不稳定型心绞痛 (UAP)患者随机分为治疗组和对照组 ,每组 40例 ,对照组予硝酸脂类、β受体阻滞剂、钙拮抗剂、阿司匹林及低分子肝素等常规药治疗。治疗组在对照组基础上加服阿托伐他汀 10mg ,Qd ,两组疗程均为 1个月。结果 治疗组心绞痛的改善程度与对照组比较有显著性差异 (P <0 .0 5 )。结论 阿托伐他汀治疗UVP ,能稳定动脉粥样硬化斑块 。
作者 杜红坤
出处 《右江医学》 2004年第6期530-531,共2页 Chinese Youjiang Medical Journal
  • 相关文献

参考文献5

二级参考文献30

  • 1[1]TREASURE C B,KLEIN J L,WEINTRAUB W S,et al.Beneficial effects of cholesterol-lowering therapy on the coronary on the endothelium in patients with coronary artery disease[J].N Engl J Med,1995,332(8):481-487.
  • 2[2]ANDERSON T,MEREDITH I,YEUNG A,et al.The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary[J].N Engl J Med,1995,332(8):488-493.
  • 3[3]DUPUIS J,TARDIF J,CERNACEK P,et al.Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes:the RECIFE(Reduction of cholesterol in Ischemia and Function of the Endothelium)trial[J].Circulation,1999,99(25):3227-3233.
  • 4[4]ULRICH L,FATA V L,PLUTZKY J,et al.Upregulation of endotheliual nitric oxide synthase by HMG CoA reductase inhibitors[J].Circulation,1998,97(12):1129-1135.
  • 5[5]LACOSTE L,LAM J Y,HUNG J,et al.Hyperlipidemia and coronary disease: correction of the increased thrombogenic potential with cholesterol reduction[J].Circulation,1995,92(1):3127-3177.
  • 6[6]RIDKER P M,CUSHSHMAN M,STAMPFER M J,et al.Inflammation,aspirin and risk of cardiovascular disease in apparently healthy men[J].N Engl J Med,1997,336(14):973-979.
  • 7[7]BICKEL C,RUPPRECHTT H J,BLANKENBERG S,et al.Non-lipid lowering effects of statin medication in patients with coronary heart disease[J].J Am Coll Cardiol,2000,35(1):256A.
  • 8[8]INOUE I,GOTO S,MIZOTANI K,et al.Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect reduction of MRNA levels for interleukin-1β,interleukin-6,cyclooxygenase-2,and p22phox by regulation of peroxisome proliferator-activated receptorα(PPARα)in primary endothelial cells[J].Life sciences,2000,67(8):863-876.
  • 9[9]SINDERMANN J,WEIGEL K,MULLER J G,et al.Induction of p53 and interleukin by HMG CoA reductase inhibitors in human coronary smooth muscle cells[J].EurHeartJ,1997,18(3):371.
  • 10Laufs U,Fata VL,Pluteky J,et al.Upregulation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors.Circulation,1998,97:1129

共引文献37

同被引文献51

引证文献2

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部