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羊膜移植联合结膜瓣遮盖治疗小儿细菌性角膜溃疡穿孔的研究 被引量:8

Amniotic membrane transplantation combined with conjunctival flap covering for t reating children bacteria corneal ulcer perforations
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摘要 目的:探讨羊膜移植联合结膜瓣遮盖治疗小儿细菌性角膜溃疡穿孔的可行性。方法:采用新鲜羊膜移植联合结膜瓣遮盖治疗小儿细菌性角膜溃疡穿孔5例(5眼),术后随访6~24mo。结果:全部患眼治愈,未见复发。术后均未见新鲜羊膜移植片急性排斥反应,炎症控制。4~5wk角膜上皮愈合,2眼视力不同程度提高。结论:羊膜移植联合结膜瓣遮盖是治疗小儿细菌性角膜溃疡穿孔的有效方法。 AIM: To evaluate the efficacy of amniotic membrane transplantation(AMT) for t reating children bacteria corneal ulcer perforations.· MEHTODS: Fresh AMT was performed in 5 patients (5 eyes) with children bacteri a corneal ulcer perforation. All the patients were followed up for 6-24mo.· RESULTS: No acute rejection was observed after fresh AMT in all patients. The infection and inflammation were controlled in all eyes after surgery. In all ey es epithelium healed over all corneal ulcer within 4-5wk and remained stable dur ing the follow-up. Visual acuity was improved in 2 eyes.· CONCLUSION: AMT is an effective method to treat children bacteria corneal ulc er perforation.·
出处 《国际眼科杂志》 CAS 2004年第4期738-740,共3页 International Eye Science
关键词 羊膜移植 结膜瓣遮盖 细菌性 角膜溃疡 穿孔 儿童 amniotic membrane transplantation conjunctival flap cover childre n bacteria corneal ulcer perforation
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  • 1Mooren A. Ophthalmiatrische Beobachtungen. Berlin: Hirschwald,1867.
  • 2Robert DY, Peter GW. Light and electron microscopy of corneal melting syndrome (Mooren's ulcer). Br J Ophthalmol, 1982;66:341-356.
  • 3Peter JB, Juan JA, Norman TF. Presence of circulating immune complexes in patients with peripheral corneal disease. Arch Ophthalmol, 1983; 0h242-245.
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  • 5Abrahan S, Daniel M, Pinnita P. Amniotic membrane grafts for nontraumatic corneal perforations, descemetoceles, and deep ulcers. Ophthalmology,2002;109(4): 694-702.
  • 6Stuart IB. Mooren's ulcer treatment by conjunctival excision. Br J Ophthalmol, 1975;59:675-682.
  • 7陈家祺,周世有,黄挺,刘祖国,陈龙山,林跃生.新鲜羊膜移植治疗严重的急性炎症期及瘢痕期眼表疾病的临床研究[J].中华眼科杂志,2000,36(1):13-17. 被引量:425
  • 8徐鼎.用于有症状的大疱性角膜病变的羊膜移植[J].美国医学会眼科杂志(中文版),2000,12(3):132-137. 被引量:4

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