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皮质类固醇激素在细菌性角膜炎中的运用 被引量:3

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摘要 目的评估皮质类固醇激素对细菌性角膜炎是否有较好疗效。方法采用双盲法对我院眼科门诊就诊且明确诊断为细菌性结膜炎的患者随机分为实验组和对照组。前者使用0.02%氟美瞳滴眼液,后者使用生理盐水滴眼。所有患者均同时接受抗生素正规治疗。实验组和对照组均又分为两个亚组,Ⅰ组为角膜溃疡中心在瞳孔区,Ⅱ组为角膜溃疡中心在瞳孔区以外。评估患者治疗前后最佳矫正视力,角膜上皮愈合时间,及可能出现的不良事件。结果实验组和对照组相比较,当角膜溃疡中心主要在瞳孔区时,实验组最佳矫正视力治疗后提高程度比对照组高,但角膜溃疡中心在瞳孔区以外时,两组视力提高程度无显著性差异。实验组角膜上皮愈合时间显著长于对照组。结论使用皮质类固醇激素治疗细菌性角膜炎,角膜上皮愈合时间延迟,角膜炎症反应减轻,对中心视力的恢复起到一定作用。
出处 《中国现代医生》 2010年第31期179-180,192,共3页 China Modern Doctor
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参考文献11

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共引文献33

同被引文献28

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