摘要
目的 :探讨新鲜羊膜移植在角膜急性炎症治疗中的抑制多形核白细胞作用 ,并与保存羊膜移植作比较。方法 :以48只新西兰大白兔制作角膜碱烧伤实验模型 ,2 4小时后设立新鲜羊膜移植组、保存羊膜移植组和对照组。术后 14天、30天取材角膜进行组织病理学检查 ,以计算机图像分析系统测量其多形核白细胞含量。结果 :新鲜羊膜移植组角膜组织中多形核白细胞含量低于保存羊膜移植组 ,两者均低于对照组 (P <0 0 1)。结论 :在角膜急性炎症期治疗中 ,新鲜羊膜移植能够抑制多形核白细胞浸润 。
Objective:To understand the effects of fresh amniotic membrane vs preserved amniotic membrane on restraining polymorphonuclear leukocyte (PMN) in acute corneal inflammation.Methods:Models of corneal alkali burn were made in 48 New Zealand white rabbits.24 hours after burn,the rabbits corneas transplanted with fresh amniotic membrane (fresh amniotic membrane transplantation group,fAMT),or preserved amniotic membrane (preserved amniotic membrane transplantation group,pAMT) and control group (C).14 and 30 days after operation,the corneal specimens were examined pathologically,and the number of PMN in corneas were measured with computer image analysis system.Results:The number of PMN in fAMT was lower than that in pAMT,and both were lower than that in C.Conclusion:Amniotic membrane transplantation can reduce the number of PMN in inflammatory cornea,and fresh amniotic membrane has stronger effects than preserved amniotic membrane in restraining inflammatory infiltration.
出处
《眼科》
CAS
2001年第4期236-238,共3页
Ophthalmology in China
