摘要
目的:为了全面反映美洲大蠊配方颗粒所含多种组分,建立美洲大蠊配方颗粒特征图谱测定方法,指导、控制美洲大蠊配方颗粒内在质量。方法:依托高效液相色谱仪,运用梯度洗脱的分析方法,建立了美洲大蠊配方颗粒特征图谱测定方法。结果:美洲大蠊配方颗粒特征图谱中呈现7个特征峰,标定了尿嘧啶、酪氨酸、次黄嘌呤、肌苷4个特征峰。结论:美洲大蠊配方颗粒特征图谱测定方法稳定、可靠,图谱反映了美洲大蠊配方颗粒的多组分面貌,具有良好的可行性,可为美洲大蠊配方颗粒的质量评价提供参考依据。
Objective:In order to comprehensively reflect the various components contained in Periplaneta Americana formula particles,a method for determining the characteristic map of Periplaneta Americana formula particles was established to guide and control the internal quality of Periplaneta Americana formula particles.Methods:Relying on HPLC liquid chromatograph,using gradient elution method,establish the determination method of Periplaneta Americana formula particles feature maps.Results:Periplaneta Americana formula particles presents seven characteristic peaks in the feature maps,calibration of uracil,tyrosine,hypoxanthine and inosine four characteristic peak.Conclusion:Periplaneta Americana formula particles feature maps determination method is stable,reliable and map reflects the Periplaneta Americana formula particles multicomponent appearance,has the good feasibility,can provide reference for quality evaluation of Periplaneta Americana formula particles.
作者
曾永祯
高晗
孙福仁
田方
李军山
Zeng Yongzhen;Gao Han;Sun Furen;Tian Fang;Li Junshan(Shenwei Pharmaceutical Group co.LTD,Shijiazhuang 051430,China;Chuxiong Shenwei Shiprui Pharmaceutical Research co.LTD,Chuxiong 675000,China)
出处
《亚太传统医药》
2021年第7期65-67,共3页
Asia-Pacific Traditional Medicine
基金
省部级重大科技专项(2019ZF008)
关键词
美洲大蠊
特征图谱
质量评价
Periplaneta Americana Formula Particles
Feature Maps
Content Determination
