Four novel organogermanium scsquioxidcs with anthraquinonc or naphthalene moiety were synthesized. The structures were characterized by IR NMR and elemental analysis, and their cytotoxicitics wcrc evaluated against hu...Four novel organogermanium scsquioxidcs with anthraquinonc or naphthalene moiety were synthesized. The structures were characterized by IR NMR and elemental analysis, and their cytotoxicitics wcrc evaluated against human chronic mycloid leukemia K562 cell lines. The cytotoxicity could bc improved by the introduction of planar aromatic chromophorc moiety to the parent compound, Ge-132.展开更多
Thirteen title compounds Ph 3GeS 2CNR 2(1—13) were synthesized by the reaction of \{corre\|\}sponding triphenylgermanium chloride with dithiocarbamates. Their structures were confirmed by elemen\|tal analysis, IR, 1H...Thirteen title compounds Ph 3GeS 2CNR 2(1—13) were synthesized by the reaction of \{corre\|\}sponding triphenylgermanium chloride with dithiocarbamates. Their structures were confirmed by elemen\|tal analysis, IR, 1H NMR, UV and MS. Some of these compounds showed antitumor activities in vitro.展开更多
文摘Four novel organogermanium scsquioxidcs with anthraquinonc or naphthalene moiety were synthesized. The structures were characterized by IR NMR and elemental analysis, and their cytotoxicitics wcrc evaluated against human chronic mycloid leukemia K562 cell lines. The cytotoxicity could bc improved by the introduction of planar aromatic chromophorc moiety to the parent compound, Ge-132.
文摘Thirteen title compounds Ph 3GeS 2CNR 2(1—13) were synthesized by the reaction of \{corre\|\}sponding triphenylgermanium chloride with dithiocarbamates. Their structures were confirmed by elemen\|tal analysis, IR, 1H NMR, UV and MS. Some of these compounds showed antitumor activities in vitro.
