As the main window for the public to understand the outside world,mass media has an undeniable influence on economic and social development.The way in which the media reports on issues related to people with disabilit...As the main window for the public to understand the outside world,mass media has an undeniable influence on economic and social development.The way in which the media reports on issues related to people with disabilities not only affects the voice of the disabled community,which determines the public image of the“disappearing”disabled community,but also affects the public awareness and recognition of the disability cause.To further explore the current status of mainstream media’s coverage of the disability cause,this article combines relevant concepts from media function theory and analyzes reports related to the integrated development of the disability cause in the Guangdong-Hong Kong-Macao Greater Bay Area by using the examples of the Zhuhai Special Zone Daily,Southern Metropolis Daily,and Shenzhen Special Zone Daily since the release of the Development Plan Outline for the Guangdong-Hong Kong-Macao Greater Bay Area in 2019.The results show that the“Integrated Development of the Disability Cause in the Bay Area”presented in the reports has the characteristics of service-oriented and cooperation-based,which is in line with the overall trend of the development of China’s disability cause.However,due to factors such as a small overall quantity of related reports,a relatively single style of reporting and information sources,and a strong promotional tone,there still exists a certain difference between the“media reality”and objective reality constructed by these reports.Therefore,this article suggests that institutional media should fully strengthen their coverage of relevant topics,while enhancing the timeliness and readability of reports by enriching various reporting elements.By further enhancing the effectiveness of reporting and communication,the integrated development of the disability cause in the Bay Area can be effectively promoted.展开更多
Objective To investigate the effect of exogenous surfactant on Eustachian tube opening function. Methods This reasarch measures for the Eustachian tube opening pressure by injection of surface active substance into m...Objective To investigate the effect of exogenous surfactant on Eustachian tube opening function. Methods This reasarch measures for the Eustachian tube opening pressure by injection of surface active substance into middle ear space, studying the effect of surfactant on Eustachian tube opening function. Results It has been showed that the injection of killed streptococcus pneumoneac bacteria by the transtympanic route, successfully developed a secretory otitis media model. Eustachian tube opening pressure in ears with SOM was significantly greater than those without effusion ( P <0.01). Irrigation the middle ear space with surfactant resulted in a dramatic decrease in eustachian tube passive opening pressure in both normal and patients ( P <0.01). Conclusion The results indicate that flushing with exogenous surfactant by the transtympanic rote reduce of eustachian tube surface tension, and it benefits the Eustachian tube opening.展开更多
This article introduces a novel low rank approximation (LRA)-based model to detect the functional regions with the data from about 15 million social media check-in records during a year-long period in Shanghai, China....This article introduces a novel low rank approximation (LRA)-based model to detect the functional regions with the data from about 15 million social media check-in records during a year-long period in Shanghai, China. We identified a series of latent structures, named latent spatio-temporal activity structures. While interpreting these structures, we can obtain a series of underlying associations between the spatial and temporal activity patterns. Moreover, we can not only reproduce the observed data with a lower dimensional representative, but also project spatio-temporal activity patterns in the same coordinate system. With the K-means clustering algorithm, five significant types of clusters that are directly annotated with a combination of temporal activities can be obtained, providing a clear picture of the correlation between the groups of regions and different activities at different times during a day. Besides the commercial and transportation dominant areas, we also detected two kinds of residential areas, the developed residential areas and the developing residential areas.We further interpret the spatial distribution of these clusters using urban form analytics. The results are highly consistent with the government planning in the same periods, indicating that our model is applicable to infer the functional regions from social media check-in data and can benefit a wide range of fields, such as urban planning, public services, and location-based recommender systems.展开更多
The expression and clinical significance of relevant cytokines in otitis media (OM) are discussed, and the alterations to the pathological state of the otitis media mucosa are further understood through the study of c...The expression and clinical significance of relevant cytokines in otitis media (OM) are discussed, and the alterations to the pathological state of the otitis media mucosa are further understood through the study of cytokine transduction pathways. More and more studies have shown that relevant cell proliferation and inflammation progression pathways play a role in the development of otitis media, such as the Jun amino-terminal protein kinase (JNK) mitogen-activated protein kinase (MAPK) signaling pathway, the NF-κB signaling pathway, and the PI3K/AKT/PTEN pathway, which are involved in the proliferation of the middle ear mucosa during otitis media, which affects the mucosal cilia, motor function, Eustachian tube function, and the mucosal ciliary function. These studies provide new ideas for the treatment of otitis media and further explore the feasibility of immunotherapy in the future treatment of otitis media. In this paper, we present a review of the latest research progress on the expression of various cytokines in otitis media.展开更多
文摘As the main window for the public to understand the outside world,mass media has an undeniable influence on economic and social development.The way in which the media reports on issues related to people with disabilities not only affects the voice of the disabled community,which determines the public image of the“disappearing”disabled community,but also affects the public awareness and recognition of the disability cause.To further explore the current status of mainstream media’s coverage of the disability cause,this article combines relevant concepts from media function theory and analyzes reports related to the integrated development of the disability cause in the Guangdong-Hong Kong-Macao Greater Bay Area by using the examples of the Zhuhai Special Zone Daily,Southern Metropolis Daily,and Shenzhen Special Zone Daily since the release of the Development Plan Outline for the Guangdong-Hong Kong-Macao Greater Bay Area in 2019.The results show that the“Integrated Development of the Disability Cause in the Bay Area”presented in the reports has the characteristics of service-oriented and cooperation-based,which is in line with the overall trend of the development of China’s disability cause.However,due to factors such as a small overall quantity of related reports,a relatively single style of reporting and information sources,and a strong promotional tone,there still exists a certain difference between the“media reality”and objective reality constructed by these reports.Therefore,this article suggests that institutional media should fully strengthen their coverage of relevant topics,while enhancing the timeliness and readability of reports by enriching various reporting elements.By further enhancing the effectiveness of reporting and communication,the integrated development of the disability cause in the Bay Area can be effectively promoted.
文摘Objective To investigate the effect of exogenous surfactant on Eustachian tube opening function. Methods This reasarch measures for the Eustachian tube opening pressure by injection of surface active substance into middle ear space, studying the effect of surfactant on Eustachian tube opening function. Results It has been showed that the injection of killed streptococcus pneumoneac bacteria by the transtympanic route, successfully developed a secretory otitis media model. Eustachian tube opening pressure in ears with SOM was significantly greater than those without effusion ( P <0.01). Irrigation the middle ear space with surfactant resulted in a dramatic decrease in eustachian tube passive opening pressure in both normal and patients ( P <0.01). Conclusion The results indicate that flushing with exogenous surfactant by the transtympanic rote reduce of eustachian tube surface tension, and it benefits the Eustachian tube opening.
基金the Open Research Fund Program of Shenzhen Key Laboratory of Spatial Smart Sensing and Services%sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry(grant number 50-20150618)%National Natural Science Foundation of China (grant numbers 41001220, 51378512, 41571397, and 41501442)This work was also supported by the Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund
文摘This article introduces a novel low rank approximation (LRA)-based model to detect the functional regions with the data from about 15 million social media check-in records during a year-long period in Shanghai, China. We identified a series of latent structures, named latent spatio-temporal activity structures. While interpreting these structures, we can obtain a series of underlying associations between the spatial and temporal activity patterns. Moreover, we can not only reproduce the observed data with a lower dimensional representative, but also project spatio-temporal activity patterns in the same coordinate system. With the K-means clustering algorithm, five significant types of clusters that are directly annotated with a combination of temporal activities can be obtained, providing a clear picture of the correlation between the groups of regions and different activities at different times during a day. Besides the commercial and transportation dominant areas, we also detected two kinds of residential areas, the developed residential areas and the developing residential areas.We further interpret the spatial distribution of these clusters using urban form analytics. The results are highly consistent with the government planning in the same periods, indicating that our model is applicable to infer the functional regions from social media check-in data and can benefit a wide range of fields, such as urban planning, public services, and location-based recommender systems.
文摘The expression and clinical significance of relevant cytokines in otitis media (OM) are discussed, and the alterations to the pathological state of the otitis media mucosa are further understood through the study of cytokine transduction pathways. More and more studies have shown that relevant cell proliferation and inflammation progression pathways play a role in the development of otitis media, such as the Jun amino-terminal protein kinase (JNK) mitogen-activated protein kinase (MAPK) signaling pathway, the NF-κB signaling pathway, and the PI3K/AKT/PTEN pathway, which are involved in the proliferation of the middle ear mucosa during otitis media, which affects the mucosal cilia, motor function, Eustachian tube function, and the mucosal ciliary function. These studies provide new ideas for the treatment of otitis media and further explore the feasibility of immunotherapy in the future treatment of otitis media. In this paper, we present a review of the latest research progress on the expression of various cytokines in otitis media.
