The flight envelope of Air Turbo Rocket(ATR)engines is broader compared to conventional aero-engines,and designing a full-envelope controller using traditional methods poses significant challenges due to a burdensome ...The flight envelope of Air Turbo Rocket(ATR)engines is broader compared to conventional aero-engines,and designing a full-envelope controller using traditional methods poses significant challenges due to a burdensome design process.To address this issue,this paper proposes a self-learning neural network controller design method based on Reinforcement Learning(RL).Additionally,a method for predictive compensation and stability rewards is proposed to reduce the system oscillation caused by actuator delay.This approach simplifies the actuator to a firstorder inertial element exhibiting pure delay.A simulation environment for the ATR engineactuator system is first established.Based on this environment,a self-learning neural network controller using a predictive compensator and the Proximal Policy Optimization(PPO)algorithm is then developed.Furthermore,the temporal difference signals from the controller output are integrated into the reward function to enhance system stability.The proposed method is validated through numerical simulations and semi-physical experiments.The numerical simulation results demonstrate that the proposed method increases the system's tolerance to delays from 20 ms to 400 ms.Under an actuator delay of 400 ms,the average steady-state error remains less than0.1%,the overshoot is limited to 1%,and the settling time does not exceed 3 s.Moreover,compared to the traditional method,the proposed method exhibits higher adaptability to model errors and variations in flight conditions.In the conducted semi-physical simulation experiments,the proposed method achieves stable control of a real electric pump.展开更多
分析初中英语阅读教学瓶颈。阐述图式理论与ATR学习模式的内涵,并优化基于图式理论的ATR学习模式,即通过激活、积累、调试、重建、延展教学活动设计,实现知识结构化学习与迁移运用,最终实现知识、能力、素养的螺旋提升。以人教版初中《...分析初中英语阅读教学瓶颈。阐述图式理论与ATR学习模式的内涵,并优化基于图式理论的ATR学习模式,即通过激活、积累、调试、重建、延展教学活动设计,实现知识结构化学习与迁移运用,最终实现知识、能力、素养的螺旋提升。以人教版初中《英语》八年级(下)Unit 7 What is the highest mountain in the world? Section A 3a—3c为例,围绕语篇Qomolangma—the most Dangerous mountain in the world探究ATR学习模式促进学生阅读的途径。展开更多
随着全球人口老龄化进程的推进,前列腺癌的发病率和死亡率逐年上升,已引起了社会各界的广泛关注。基于合成致死策略,美国食品药品监督管理局(Food and Drug Administration, FDA)近年来已相继批准了多项多聚腺苷二磷酸核糖聚合酶(poly A...随着全球人口老龄化进程的推进,前列腺癌的发病率和死亡率逐年上升,已引起了社会各界的广泛关注。基于合成致死策略,美国食品药品监督管理局(Food and Drug Administration, FDA)近年来已相继批准了多项多聚腺苷二磷酸核糖聚合酶(poly ADP-ribose polymerase, PARP)抑制剂,用于转移性去势抵抗性前列腺癌(metastatic castration-resistant prostate cancer,mCRPC)的治疗。这一进展极大地激发了学者们对新型合成致死组合——共济失调毛细血管扩张突变(ataxia telangiectasia-mutated, ATM)基因/共济失调毛细血管扩张和Rad3相关激酶(ataxia telangiectasia and Rad3-related protein,ATR)的研究兴趣。在DNA损伤修复通路中,ATM激酶主要参与DNA双链断裂的修复,而激酶ATR则在DNA单链断裂的修复过程中发挥重要作用,并起到积极的调控作用。ATR抑制剂被认为是继PARP抑制剂之后,最具前景的合成致死靶向药物之一,有望成为ATM基因突变患者的潜在新型治疗药物。然而,目前关于ATR抑制剂在前列腺癌治疗领域的临床研究数据尚显不足。因此,深入理解ATM/ATR激酶组合的合成致死机制,对于推进前列腺癌的精准治疗具有至关重要的意义。展开更多
基金co-supported by the National Science and Technology Major Project(No.J2019-Ⅲ-0010-0054)the National Natural Science Foundation of China(No.52336002)。
文摘The flight envelope of Air Turbo Rocket(ATR)engines is broader compared to conventional aero-engines,and designing a full-envelope controller using traditional methods poses significant challenges due to a burdensome design process.To address this issue,this paper proposes a self-learning neural network controller design method based on Reinforcement Learning(RL).Additionally,a method for predictive compensation and stability rewards is proposed to reduce the system oscillation caused by actuator delay.This approach simplifies the actuator to a firstorder inertial element exhibiting pure delay.A simulation environment for the ATR engineactuator system is first established.Based on this environment,a self-learning neural network controller using a predictive compensator and the Proximal Policy Optimization(PPO)algorithm is then developed.Furthermore,the temporal difference signals from the controller output are integrated into the reward function to enhance system stability.The proposed method is validated through numerical simulations and semi-physical experiments.The numerical simulation results demonstrate that the proposed method increases the system's tolerance to delays from 20 ms to 400 ms.Under an actuator delay of 400 ms,the average steady-state error remains less than0.1%,the overshoot is limited to 1%,and the settling time does not exceed 3 s.Moreover,compared to the traditional method,the proposed method exhibits higher adaptability to model errors and variations in flight conditions.In the conducted semi-physical simulation experiments,the proposed method achieves stable control of a real electric pump.
文摘分析初中英语阅读教学瓶颈。阐述图式理论与ATR学习模式的内涵,并优化基于图式理论的ATR学习模式,即通过激活、积累、调试、重建、延展教学活动设计,实现知识结构化学习与迁移运用,最终实现知识、能力、素养的螺旋提升。以人教版初中《英语》八年级(下)Unit 7 What is the highest mountain in the world? Section A 3a—3c为例,围绕语篇Qomolangma—the most Dangerous mountain in the world探究ATR学习模式促进学生阅读的途径。
