Objective: to further improve the rationality of the use of antibacterial drugs in hospital, and to deeply analyze the practical application effect and value of pharmaceutical affairs management in pharmacy department...Objective: to further improve the rationality of the use of antibacterial drugs in hospital, and to deeply analyze the practical application effect and value of pharmaceutical affairs management in pharmacy department. Methods: 300 prescriptions containing antibacterial drugs in our hospital from January 2020 to January 2021 were collected as research samples, and were randomly divided into the control group (n = 150, traditional pharmaceutical management) and the observation group (n = 150, rational drug use management) according to the standards. The irrational drug use of antibacterial drugs in the two groups was compared in terms of cost and use time. Results: through observation and research, it was found that the incidence of irrational use of antibacterial drugs in the observation group was significantly better than that before the implementation of the management, and was better than that in the control group at the same time (P < 0.05). And from the perspective of the cost and use time of antibacterial drugs, the cost and treatment time of the observation group were significantly reduced and shortened (12.4±3.2) d and (648.6±56.2) Yuan after the implementation of rational drug use management. The overall treatment cost and treatment time of the observation group were lower than those of the control group (P < 0.05). Conclusion: the rational administration of antibacterial drugs is actively applied in the pharmacy department, which can ensure the rationality of the application of antibacterial drugs, shorten and reduce the use time of antibacterial drugs and the incidence of adverse drug events to a certain extent.展开更多
Soil moisture(SM)is a critical variable in terrestrial ecosystems,especially in arid and semi-arid areas where water sources are limited.Despite its importance,understanding the spatiotemporal variations and influenci...Soil moisture(SM)is a critical variable in terrestrial ecosystems,especially in arid and semi-arid areas where water sources are limited.Despite its importance,understanding the spatiotemporal variations and influencing factors of SM in these areas remains insufficient.This study investigated the spatiotemporal variations and influencing factors of SM in arid and semi-arid areas of China by utilizing the extended triple collation(ETC),Mann-Kendall test,Theil-Sen estimator,ridge regression analysis,and other relevant methods.The following findings were obtained:(1)at the pixel scale,the long-term monthly SM data from the European Space Agency Climate Change Initiative(ESA CCI)exhibited the highest correlation coefficient of 0.794 and the lowest root mean square error(RMSE)of 0.014 m^(3)/m^(3);(2)from 2000 to 2022,the study area experienced significant increase in annual average SM,with a rate of 0.408×10^(-3)m^(3)/(m^(3)•a).Moreover,higher altitudes showed a notable upward trend,with SM increasing rates at 0.210×10^(-3)m^(3)/(m^(3)•a)between 1000 and 2000 m,0.530×10^(-3)m^(3)/(m^(3)•a)between 2000 and 4000 m,and 0.760×10^(-3)m^(3)/(m^(3)•a)at altitudes above 4000 m;(3)land surface temperature(LST),root zone soil moisture(RSM)(10-40 cm depth),and normalized difference vegetation index(NDVI)were identified as the primary factors influencing annual average SM,which accounted for 34.37%,24.16%,and 22.64%relative contributions,respectively;and(4)absolute contribution of LST was more significant in subareas at higher altitudes,with average absolute contributions of 0.800×10^(-3)m^(3)/(m^(3)•a)between 2000 and 4000 m and 0.500×10^(-2) m^(3)/(m^(3)•a)above 4000 m.This study reveals the spatiotemporal variations and main influencing factors of SM in Chinese arid and semi-arid areas,highlighting the more pronounced absolute contribution of LST to SM in high-altitude areas,providing valuable insights for ecological research and water resource management in these areas.展开更多
文摘Objective: to further improve the rationality of the use of antibacterial drugs in hospital, and to deeply analyze the practical application effect and value of pharmaceutical affairs management in pharmacy department. Methods: 300 prescriptions containing antibacterial drugs in our hospital from January 2020 to January 2021 were collected as research samples, and were randomly divided into the control group (n = 150, traditional pharmaceutical management) and the observation group (n = 150, rational drug use management) according to the standards. The irrational drug use of antibacterial drugs in the two groups was compared in terms of cost and use time. Results: through observation and research, it was found that the incidence of irrational use of antibacterial drugs in the observation group was significantly better than that before the implementation of the management, and was better than that in the control group at the same time (P < 0.05). And from the perspective of the cost and use time of antibacterial drugs, the cost and treatment time of the observation group were significantly reduced and shortened (12.4±3.2) d and (648.6±56.2) Yuan after the implementation of rational drug use management. The overall treatment cost and treatment time of the observation group were lower than those of the control group (P < 0.05). Conclusion: the rational administration of antibacterial drugs is actively applied in the pharmacy department, which can ensure the rationality of the application of antibacterial drugs, shorten and reduce the use time of antibacterial drugs and the incidence of adverse drug events to a certain extent.
基金supported by the Natural Science Foundation of Henan Province(252300421290)the National Natural Science Foundation of China(41771438)+1 种基金the Program for Innovative Research Team(in Science and Technology)of Henan University(22IRTSTHN010)the Postgraduate Education Reform and Quality Improvement Project of Henan Province(HNYJS2020JD14).
文摘Soil moisture(SM)is a critical variable in terrestrial ecosystems,especially in arid and semi-arid areas where water sources are limited.Despite its importance,understanding the spatiotemporal variations and influencing factors of SM in these areas remains insufficient.This study investigated the spatiotemporal variations and influencing factors of SM in arid and semi-arid areas of China by utilizing the extended triple collation(ETC),Mann-Kendall test,Theil-Sen estimator,ridge regression analysis,and other relevant methods.The following findings were obtained:(1)at the pixel scale,the long-term monthly SM data from the European Space Agency Climate Change Initiative(ESA CCI)exhibited the highest correlation coefficient of 0.794 and the lowest root mean square error(RMSE)of 0.014 m^(3)/m^(3);(2)from 2000 to 2022,the study area experienced significant increase in annual average SM,with a rate of 0.408×10^(-3)m^(3)/(m^(3)•a).Moreover,higher altitudes showed a notable upward trend,with SM increasing rates at 0.210×10^(-3)m^(3)/(m^(3)•a)between 1000 and 2000 m,0.530×10^(-3)m^(3)/(m^(3)•a)between 2000 and 4000 m,and 0.760×10^(-3)m^(3)/(m^(3)•a)at altitudes above 4000 m;(3)land surface temperature(LST),root zone soil moisture(RSM)(10-40 cm depth),and normalized difference vegetation index(NDVI)were identified as the primary factors influencing annual average SM,which accounted for 34.37%,24.16%,and 22.64%relative contributions,respectively;and(4)absolute contribution of LST was more significant in subareas at higher altitudes,with average absolute contributions of 0.800×10^(-3)m^(3)/(m^(3)•a)between 2000 and 4000 m and 0.500×10^(-2) m^(3)/(m^(3)•a)above 4000 m.This study reveals the spatiotemporal variations and main influencing factors of SM in Chinese arid and semi-arid areas,highlighting the more pronounced absolute contribution of LST to SM in high-altitude areas,providing valuable insights for ecological research and water resource management in these areas.
