摘要
现有的一些用于动脉粥样硬化斑块诊断的检测方法如X线血管造影、血管内超声、光学相干体层扫描、B鄄型超声、电子束CT、核磁共振、拉曼光谱学检查和温度测量法等,在显示血管腔狭窄、管壁增厚、斑块体积以及斑块成分等方面各有其独特价值。但是,它们或因是创伤性检查、或因为检查本身的局限性(如只能显示钙化)、或不能早期发现以代谢紊乱为特征的病变,因而限制了它们在临床上的广泛应用。利用核素标记参与动脉粥样硬化的中间物质进行显像,可以精确、定量反映斑块成分和代谢情况,为无创伤性显示动脉粥样硬化斑块带来了希望,在疾病筛选、治疗决策、疗效观察以及随访研究上具有广阔的应用前景。
The available detecting methods such as X-ray angiography, IVUS, OCT, B-Mode ultrasound, EBCT, MRI, thermometry all have their special value in displaying vascular constriction, thickening and plaque volume when used in the diagnosis of atherosclerotic plaque. The extensive application on clinic is limited because of either the invasive feature, or the limitation that only can displaying calcification, or the method, which can't reveal the early stage lesion characterized by metabolism disorder. The imaging using the nuclide labeled substance participating in atherosclerosis can reveal plaque components and metabolism status precisely and quantificationally, which brings in promise of noninvasively displaying atherosclerotic plaque, and has expansive application foreground in disease screening, therapeutic decision-making, effect observation and follow-up study.
出处
《国外医学（放射医学核医学分册）》
2004年第3期109-113,共5页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
