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颈动脉粥样硬化与脑梗死的相关研究 被引量:15

Carotid atherosclerosis in patients with cerebral infraction
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摘要 目的 探讨脑梗死患者颈动脉粥样硬化病变特点及其与脑梗死之间的关系 ,寻找颈动脉斑块的主要危险因素及潜在的临床标志物。方法 对 12 0例脑梗死患者进行颈动脉超声检查 ,根据颈动脉超声结果分为斑块组和非斑块组。结果  87例患者 ( 72 .5 % )检出颈动脉粥样硬化斑块 ,颈动脉重度狭窄发生率为 4.17%。梗死侧颈动脉软斑发生率高于非梗死侧 ( 3 2 .9%∶16.9% ) ,斑块组年龄、TC水平、高血压患者比例明显高于非斑块组 ,分别为 ( 65 .2 4± 9.69∶5 5 .3 8± 14 .5 1,P =0 .0 0 7) ,( 6.0 4± 1.18∶5 .41± 0 .79,P =0 .0 2 7) ,( 4 7/63∶10 /2 1,P =0 .0 2 2 )。结论 我国缺血性脑卒中患者颈动脉粥样硬化病变特点可能以斑块居多 ,而重度狭窄发生率较低 。 Objective The present study was designed to assess the character of carotid atherosclerosis in patients with cerebral infarction and the reationship between them;to explore the principal risk factors of carotid plaques.Methods The carotid arteries of all the 120 patients with cerebral infarction were examined by color dopper ultrasonography.According to the outcome,84 patients were included and were divided into plaque group and nonplaque group.Results Carotid plaques were found in 87 (72.5%)patients,the prevalence of severe lumen stenosis was 4.17%.The incidence of soft plaque were higher in infraction side than noninfraction side.Age,total cholesterol lever and incidence of hypertensive were significantly higher in plaque group than those in the nonplaque group,(65.24± 9.69∶55.38± 14.51,P=0.007),(6.04±1.18∶5.41±0.79,P=0.027),(47/63∶10/21,P=0.022).Conclusion The character of carotid atherosclerosis in patients with cerebral infraction in our country maybe high incidence of plaque but rare severe lumen stenosis.Soft plaque is an important risk factor of stroke.
作者 杨波
机构地区 湖北省中山医院
出处 《临床内科杂志》 CAS 北大核心 2004年第8期545-547,共3页 Journal of Clinical Internal Medicine
关键词 脑梗死 颈动脉粥样斑块 超声 Cerebral infarction Carotid plaque Ultrasonography
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