摘要
本文观察了小容量(4ml/kg)高渗氯化钠(7.5％NaCl)溶液和治疗量(相当于失血量的1.5倍)的等渗NaCl(0.9％,33ml/kg)溶液治疗早期家兔失血性休克的疗效。结果显示高渗液和治疗量的等渗液对休克时的血液动力学均有明显的影响。但治疗后2h的中心静脉压(CVP)水平和动物存活时间,高渗液优于等渗液。从而说明在早期休克的救治中,不仅与输液的Na^+量有关,更与Na^+浓度有关;这进一步验证了小容量高渗NaCl溶液治疗早期失血性休克具有独特的效果。
Hcmorrhagic shock was induced in rabbits by controlling arterial bleeding, reducing and maintaining mean arterial blood prcsurc at 5.3 kPa for 30 min. The rabbits were then given NaClsolution i.v.(1)Hypertonic NaCl group(HS)(n = 8):7.5%NaCl, 4ml/kg; (2)Isotonic NaCl solution treated group (IST) (n = 8) :0.9% NaCl, 33ml/kg; (3) Isotonic NaCl solution group (IS) (n = 8): 0.9% NaCl, 4ml/kg. The results showed that hcmodynamics (MAP,LVP, + dp/dtmax and CVP) in HS and IST group were greatly improved as compared with IS groups. It was found that CVP in HS group was higher than that in IST group 2 hours after treatment,and the survival time of rabbits was longer. It is suggessted that the small - volume hypcrtonic NaCl solution in treatment of early hcmorrhagic shock is of value .
出处
《蚌埠医学院学报》
CAS
1993年第1期13-15,共3页
Journal of Bengbu Medical College
关键词
高渗盐
氯化钠
休克
血液动力学
hypcrtonic NaCl solution
shock
hcmonhagic
rabbit
