摘要
本文以小鼠骨髓细胞姊妹染色单体互换(SCE)试验为指标,观察了人参二醇组皂甙(PDS)对访变剂环磷酰胺诱发的小鼠骨髓细胞SCE频率的影响。结果表明,在一定剂量范围内,PDS对环磷酰胺诱发的 SCE频率有明显的抑制作用,提示PDS具有抗诱变作用。
The effect of PDS on CPA induced sister chromatid exchanges (SCE) in marrow cells of mice in vivo was observed. The results showed that PDS at a fit range of dose decreased significantly the SCE frequencies induced by CPA in the marrow cells of mice. These results indicate that PDS is an antimutagen.
出处
《白求恩医科大学学报》
CSCD
1993年第4期327-328,共2页
Journal of Norman Bethune University of Medical Science
关键词
人参
皂甙
抗诱变
染色体畸变
SCE
ginseng saponins/PD
antimutagenesis"
sister chromatid exchange/DE
mu-tagenicity tests/MT
