摘要
目的测定几种民间药用植物对酪氨酸酶活性的影响。方法选用24种植物,以多巴为底物,加入植物提取物和蘑菇酪氨酸酶,测定A475,计算酪氨酸酶的抑制百分率。结果与古方中常用的增白药相比,繁缕的抑制百分率最高,绞股蓝、猪秧秧也有抑制作用。结论繁缕对酪氨酸酶有明显的抑制性,提示它对皮肤有增白效果。
Objective To test the effects of extracts from several popular plants used for curing skin disease (dermatosis) on tyrosinase activity. Methods 24 kinds of plant were selected,using DOPA as substrate, adding plant extracts and mushroom tyrosinase,measuring A475 and calculating the percentage inhibition of tyrosinase. Results Comparing with the traditional skin whitening crude drugs in Chinese ancient prescriptions,Stellaria media (L.) has the strongest inhibitory effect,and Gynostemma pentaphyllum(Thunb.)Makino and Galium aparine L,are also inhibit the activity of tyrosinase. Conclusion According to its obvious inhibitory effect on tyrosinase,we guess that S. Media (L.) has whitening effect on skin.
出处
《中国美容医学》
CAS
2004年第3期287-289,共3页
Chinese Journal of Aesthetic Medicine
