摘要
本文研究了细菌超氧化物歧化酶(b-SOD)对8 Gyγ射线照射小鼠的辐射防护作用。结果表明,辐照前后注射过b-SOD的小鼠,其存活率分别提高50％和30％。辐照前注射b-SOD还可提高骨髓细胞和脾脏淋巴细胞的DNA合成率,降低细胞膜的脂质过氧化和结构损伤。同时还对b-SOD的辐射防护作用的机理作了讨论。
The radioprotective effects of bacterial superoxide dismtitase(b-SOD) on the mice irradiated by 8 Gy γ-ray were investigated. The results showedthat when b-SOD was injected before and after irradiation, the surviral fraction ofmice is increased 50% and 30% respectively. The former treatment could increase theDNA sythesis of the myeloid cells and spleen's lymphocytes, decrease the LPO of tissuehomogenates and the haemolysis of erythrocytes significantly. The mechanism thatb-SOD can drop the radiation injury of the mice was discussed.
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
1992年第3期138-142,共5页
Journal of Radiation Research and Radiation Processing
关键词
Γ辐射
b-SOD
辐射防护
动物
γ-radiation
Surviral fraction
Bacterial superoxide dismutase (b-SOD)
Radioprotetcive effects
