摘要
目的 探讨老年期抑郁症病人的认知功能状况。方法 按CCMD - 3中心境障碍抑郁发作诊断标准 ,收集 33例 6 0岁以上首次抑郁发作的病人 (抑郁组 ) ,32名健康老年人 (对照组 )。使用HAMD、HAMA和MMSE量表对所有入组者进行评定 ,并作P30 0测定。结果 抑郁组MMSE总分低于对照组。抑郁组N2和P3潜伏期比对照组延长 ;抑郁组的P30 0潜伏期N2和P3与HAMD的迟缓因子分呈正相关 ,与MMSE总分呈负相关。结论 老年期抑郁症病人存在认知功能障碍。
Objective To explore cognitive function in elderly depressed patients.Methods 33 elderly people(aged over 60)(depression group) with the first episode of depression diagnosed according to CCMD-3 and elderly healthy people (aged over 60)(control group) were investigated.All subjects were interviewed in semi-structured manner with common data and case history questionnaire,HAMD,HAMA,MMSE,and measured event-related potentials.Results The score of MMSE was significantly lower in depression group than in control group.N2 and P3 latency in depression group were significantly longer than those in control group.In elderly depressed patients,N2 and P3 latency were positively related to psychomotor retardation item of HAMD,but negatively related to score of MMSE.Conclusion Elderly depressed patients have cognitive dysfunction.
出处
《四川精神卫生》
2004年第1期17-19,共3页
Sichuan Mental Health
基金
苏州市 2 0 0 2年度第一批指导性科技 (社会发展 )项目(SSZ0 2 2 7)
关键词
老年期抑郁症
认知功能
事件相关电位
Elderly depressed patient Cognitive function Event-related potential P300
