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成都地区汉族群体纤维蛋白溶酶原的遗传多态性 被引量:1

GENETIC POLYMORPHISM OF HUMAN PLASMINOGEN (PLG) OF HAN POPULATION, IN CHENGDU, CHINA
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摘要 应用等电聚焦免疫固定技术,调查了成都地区203名无血缘关系汉族青年男女的纤维蛋白溶酶原表现型。结果A占92.12%,AM5占4.93%,AB占1.97%,AB2占0.98%,由此求得PLG基因频率为:PLG*A为0.9606,PLG*M为50.0246,PLG*B为0.0099,PLG*B为20.0049。结果提示PLG*M5可能是蒙古人种特有的遗传标记。 The distribution of phenotypes and gene frequencies of plasminogen was studied in 203 blood donors of the Han population, Chengdu, China using isoelectric focusing followed by immunofixation. The results were PLG A=92.12% PLG AM_5=4.39%, PLG AB=1.97% and PLG AB_2=0.98%. Their gene frequencies were:PLG·A=0.9606, PLG·M_5=0.0246, PLG·B=0.0099 and PLG·B_2=0.0049. PLG·M_5 may be the specific genetic marker of the Mongoloids.
出处 《中华医学遗传学杂志》 CAS CSCD 北大核心 1992年第2期78-80,共3页 Chinese Journal of Medical Genetics
关键词 血纤维蛋白 溶酶原类 多态现象 Plasminogen Polymor phism (Genetics) Isoelectric focusing
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  • 1Toshinori Nishigaki,Keiichi Omoto. Genetic polymorphism of human plasminogen in Japanese: Correspondence of alleles thus far reported in Japanese and difference of activity among phenotypes[J] 1982,The Japanese Journal of Human Genetics(4):341~348
  • 2Shigeki Nakamura,Kazue Abe. Genetic polymorphism of human plasminogen in the Japanese population: New plasminogen variants and relationship between plasminogen phenotypes and their biological activities[J] 1982,Human Genetics(1):57~59

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