摘要
Aim To investigate the active constituents responsible for thepharmacological activities of Angelica sinensis (Oliv) Diels. Methods Chromatography was used toisolate chemical components, and spectroscopy was used to identify their structures. Results Sevencompounds were isolated and their structures were identified as ferulic acid (1), conife-rylferukte(2) , bis (2-ethylhexyl) phthalate (3), dibutyl phthalate (4), lignoceric acid (5), palmitic acid(6), and Z-6, 7-cis-dihydroxyligustilide (7) Conclusion Bis (2-ethylhexyl) phthalate and dibutylphthalate were obtained from Angelica sinensis for the first time.
目的 研究当归的化学成分 ,以了解该药药理作用的物质基础 ,并为其临床用药和进一步开发利用提供依据。方法 利用多种色谱方法分离纯化 ,通过理化常数和波谱分析鉴定其化学结构。结果 从当归根乙醇提取物中分离 7个化合物并鉴定了结构 ,分别为 :(1)阿魏酸 ,(2 )阿魏酸松伯醇酯 ,(3 )邻苯二甲酸 -2 -乙基己酯 ,(4)邻苯二甲酸二丁酯 ,(5)木蜡酸 ,(6)棕榈酸 ,(7)Z -6,7-顺式 -二羟基藁苯内酯。结论 邻苯二甲酸 -2