摘要
复方对乙酰氨基酚片中对乙酰氨基酚、阿斯匹林、咖啡因三种组分在零阶导数光谱中吸收峰重叠,本文用零交二阶导数结合联立方程组法,不经分离,直接同时测定。本法快速、准确、计算比较简单。三批模拟粉料与三批生产样品测定结果都比较满意,并与山东省药品标准的容量分析法相符合。
The zero--order derivative absorption spectra of aspirin, paracetamol and caffeineare closely overlapping. In this paper, a zero--crosssing derivative spectrophotometry combined withsimultaneous equations is proposed for the determination of the three components in a mixture withoutthe need of prior separation. Satisfactory results were obtained. The method is reproducible, accurateand rapid. Calculation is not complicated. This method could be applied to biological fluid analysis.
出处
《药学学报》
CAS
CSCD
北大核心
1992年第9期701-704,共4页
Acta Pharmaceutica Sinica
关键词
零交导数光谱
对乙酰氨基酚
Zero-crossing derivative spectrophotometry
Paracetamol
