摘要
目的 :了解过敏性紫癜 (HSP)患儿血D—二聚体的水平及其临床价值。方法 :用单克隆抗体乳胶凝集试验法测定 32例HSP患儿血D—二聚体水平 ,同时测凝血象。结果 :所有患儿凝血象正常 ,紫癜性肾炎组血浆D—二聚体阳性率显著高于无肾炎组 (P <0 .0 5 )。结论 :D—二聚体的测定能早期、快速、准确的判断HSP患儿体内的高凝状态程度 ,以便及时有效地使用抗凝药物阻止或延缓毛细血管血栓形成 ,对减轻并发症 ,缩短病程 ,防止复发十分重要。
Objective: To evaluate the plasma level and clinical volume of D-dimers in children with Henoch-Schonlein purpura(HSP). Methods:The plasma levels of D-dimers in 32 HSP patients were measured by monoclonal antibody latex agglutination test, to detect hemocoagulation at the same time. Results: The hemocoagulation in all patients is normal, the positive rate of plasma D-dimer increased significantly in patients with Henoch-Schonlein Nephritis than those in patients without Henoch-Schonlein Nephritis(P<0.05). Conclusion: The detection of plasma D-dimers makes it early,fast and exact to judge the body's hypercoaguliability degrees in the patients with HSP , so that anticoagulative drugs can be effectively used to hold back or delay the capillary vessel thrombosis in time. It is important for alleviating complications,shortening course of disease and preventing relapse.
出处
《河北医学》
CAS
2003年第12期1071-1073,共3页
Hebei Medicine
关键词
过敏性紫癜
D-二聚体
高凝状态
儿童
Henoch-Schonlein purpura
D-dimer
Hypercoaguliability
Child
