摘要
目的:探讨如何提高晚期宫颈癌的疗效和生存率。方法:将1996年1月～2000年7月我院放射治疗的晚期宫颈癌中阴道浸润呈团块、空洞状或宫旁浸润灶大于3cm的患者随机分成单纯放疗组和放疗同步化疗组,并将两组的治疗效果和不良反应相比较。结果:单纯放疗组CR为41.82%,PR为58.18%,5年生存率为29.09%;放疗同步化疗组CR为71.05%,PR为28.95%,5年生存率为56.58%;两组相比有显著性差异(χ2=9.7398,P<0.01),但两组不良反应无显著差异。结论:对阴道或宫旁浸润呈团块状的晚期宫颈癌患者,放疗同步化疗可明显提高肿瘤控制率和5年生存率,不良反应并无明显增加。
Objective:To evaluate how to improve the treraputic effect and survival rate of advanced cervical cancer.Methods:The patients from January1996to July2000in our study were advanced cervical cancer with vaginal infiltration which is like mass and cavity,or infiltri-tion beside uterus which is more than3cm in size.They were divided randomly into radiothera-py alone group and radiotherapy concurrent chemotherapy group.The effect and toxicity-side ef-fect were compared.Results:In radiotherapy group CR is41.82%and PR is58.18%.The five-year survival rate is29.09%.In radiotherapy concurrent chemotherapy group CR is71.05%and PR is28.95%,The five-year survival rate is56.58%.There is significant difference in two groups(χ 2 =9.7398,P<0.01),but there is no significant difference in toxicity-side effect.Conclu-sion:In patients suffering from advanced cervical cancer with vaginal or beside uterus infiltrition which is like mass radiotherapy concurrent chemotherapy can significantly improve the rate of controllment and five-year survival rate and has little increase in toxicity-side effect.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2003年第10期715-717,共3页
Chinese Journal of Clinical Oncology
关键词
晚期宫颈癌
放疗同步化疗
疗效
不良反应
Advanced cervical cancer Radiotherapy concurrent with chemotherapy Treraputic effect Adverse effect
