摘要
目的 研究周边虹膜切除术对泪膜的影响。方法 急性闭角型青光眼 12 6例 ,一只眼接受周边虹膜切除术 ,另一只眼点 1%匹罗卡品。治疗后观察受检者的症状和体征 ,包括畏光、眼痒、异物感、烧灼感、干涩感、视疲劳、结膜充血、角膜丝状物、Schirm e 试验、泪膜破裂时间 (BUT)、角膜荧光素染色情况。用 TMS- 1角膜地形图对其中的 82人角膜表面规则指数和角膜表面不对称指数进行测定。以 t检验比较手术组和药物组症状、体征和干眼症诊断性试验结果的差异性 ,以 χ2检验比较手术组和药物组干眼症发生率的差异性。结果 手术组与药物组在青光眼的类型、病程、年龄、性别等方面差异无显著性 ,手术组干眼的症状及体征比药物组明显 ,手术组 Schirmer 试验及 BU T测定明显低于药物组 ,角膜染色试验手术组比药物组严重 ,手术组干眼症的发生率明显高于药物组 ,所有这些差异均有统计学意义。结论 周边虹膜切除术能引起泪膜功能受损 ,使泪膜稳定性受到破坏。
Objective To investigate the influence of tear secretion and tear film stability due to iridectomy.Method The iridectomy was performed on one eye of 126 cases with minor attacks of the primary angle-closure glaucoma(Surgical group) and 1% pilocapine solution was administered on the contralateral eye (Medicinal group).The observed symptoms included photophobia,itch,ocular foreign body sensation,burning,dryness,asthenopia.The observed signs included conjunctival hyperemia,discharge,the results of 3 kinds of clinical examination for dry eye (Schirmer I test,tear film break-up time (BUT),and fluorescein staining of cornea).The surface regularity index (SRI),surface asymmetry index (SAI),the indices of TMS-1 corneal topography system were used to investigate the regularity of corneal surface in 82 patients.their results were compared with that of contralateral eye.The results were statistically analysed.Results There was no significant difference between both groups in the types of glaucoma,attacked histories,ages,and sex.The subjective complaints of dry eye were more severe in surgical group.There were obvious decreases in the Schirmer I test and BUT in surgical group.The fluorescein staining of the cornea was obvious in surgical group.The incidence in dry eye was higher in surgical group.these differences both groups were statistically significant (P<0.01).Conclusion The iridectomy can lead to the decrease of tear secretion and instability of tear film.It is helpful to use of artificial tear for the cases to improve the conditions of dry eye.
出处
《临床眼科杂志》
2003年第6期489-491,共3页
Journal of Clinical Ophthalmology
