期刊文献+

急性脑梗死胰岛素抵抗和皮质醇变化的临床意义探讨 被引量:3

To explore the clinical significance of insulin resistance and hydrocortisone changes in acute cerebral infarct
暂未订购
导出
摘要 目的 探讨急性脑梗死患者胰岛素抵抗和皮质醇变化的临床意义。方法 回顾分析64例脑梗死患者空腹血糖、胰岛素及皮质醇 ,并与健康体检对照组比较。结果 脑梗死患者血糖、胰岛素和皮质醇均较对照组高 ,ISI较对照组低 ,差异有显著性 ;血糖、胰岛素和皮质醇在合并糖尿病者较不合并糖尿病的要高、发生在半球者较发生在基底节区者要高 ,差异也有显著性。结论 IR存在于脑梗死患者 ,并与梗死部位和有否合并糖尿病有关。皮质醇与IR相关。 Objective To explore the clinical significance of insulin resistance(IR)and hydrocortisone in acute cerebral infarct. Methods The level of blood glucose on an empty stomach,free insulin and hydrocortisone of64cases acute cerebral infarct patients were analyzed retrospectively and compared to those in normal control group. Results the level of blood glucose on an empty stomach,free insulin and hydrocortisone were significantly higher and insulin sensibility index(ISI)was significantly lower in patients with acute cerebral infarct group than those in normal control group.They were also significantly higher in infarct taking place in hemisphere than those in basipodite area. Conclusion IR existed in acute cerebral infarct patients and which is correlative with infarct stop and accompanying diabetes mellitus.contisol is also correlative with IR.
作者 吴晨娟
出处 《浙江临床医学》 2003年第11期808-809,共2页 Zhejiang Clinical Medical Journal
关键词 急性脑梗死 胰岛素抵抗 皮质醇 糖尿病 acute cerebral infarct insulin resistance insulin sensibility index hydrocortisone Contisol
  • 相关文献

参考文献6

二级参考文献9

  • 1边连防,黄桂芬,陈晓红.血糖水平对脑梗塞的影响[J].中华内科杂志,1995,34(8):522-524. 被引量:85
  • 2刘群,郭颂,刘松,徐敏贤.胰岛素治疗脑血管病疗效观察[J].中风与神经疾病杂志,1997,14(1):50-51. 被引量:27
  • 3 2,Els T,Rother J,Beaulieuc,et al.Hyperglycemia delays terminal depolarization andenhances repolarization after peri-infarct spreading depression as measured by serialdiffusion MR mapping.J Cereb Blood Flow Metab,1997,17(5):591-605 3,Myers RE,Yamaguchi S.Nervous system effect of cardiac arrest in monkeys.ArchNeurol,1997,34(1):65-74
  • 4 4,Berger L,Hakim AM.The association of hyperglycemia with cerebral edema instroke.Stroke,1986,17(5):865-871
  • 5 5,Kawai N,Keep RF,Betz AL.Hyperglycemia and the vascular effect of cerebral ischemiastroke.Stroke,1997,28(1):149-154
  • 6 6,Coms DJ,Reuland AS,Martin DB,et al.Glycemic inhibition by 2-deoxyglucose reduceshyperglycemia-associated mortality and morbidity in the ischemia rats.Stroke,1986,17(5):989-903
  • 7 8,Welsh FA,Sims RE,Mckee AE,et al.Effect of glucose on recovery metabolism followinghypoxia-oligemia mouse brain:dose dependence and carbohydrate specificity.J Cereb BloodFlow Metab,1983,3(4):486-492
  • 8张晨,韩仲岩,杨开宇.急性脑梗塞患者血糖水平与梗塞灶大小的临床观察[J].中国神经精神疾病杂志,1990,16(2):111-112. 被引量:24
  • 9曹秉振,张福洲,郭述苏,耿明,张培忠.血糖水平对大鼠急性脑缺血电镜酶细胞化学及超微结构的影响[J].中国神经精神疾病杂志,1992,18(4):193-195. 被引量:50

共引文献2183

同被引文献23

引证文献3

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部