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人胎儿胃肠道5-HT 免疫活性细胞的个体发生研究——免疫组织化学观察 被引量:10

ONTOGENETIC STUDIES OF 5-HT IMMUNOREACTIVE CELLS IN THE HUMAN FETAL GUT——AN IMMUNOHISTOCHEMICAL OBSERVATION
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摘要 本研究对60例8周至足月人胎儿胃肠道5-HT 免疫活性细胞(EC 细胞)用兔抗5-HT血清做了免疫金银及 PAP 染色。结果表明,EC 细胞最早见于8周人胚十二指肠上皮,12周后在胃肠道全长均可见到。各时期胎儿胃肠道 EC 细胞的数量(以有核 EC 细胞数/视野计数)由多至少,依次为十二指肠、空肠、回肠、阑尾、结肠及胃。胃窦中 EC 细胞常具有细长突起与邻近腺细胞相接触。除胃体中 EC 细胞多为闭合型外,其余部位的 EC 细胞多为开放型。在阑尾上皮及肠腺中还可见到紧密相贴、聚集成群的 EC 细胞。 5-HT immunoreactive cells(EC cells)in the gastrointestinal tract were studied by immunogold silver staining method and PAP method in sixty human fetuses aged 8-38 weeks of gestation.The results indicated that the appearance of EC cells was as early as 8 weeks of gestation in the epithelium of duodenum.After 12 weeks of gestation,the EC cells can be found in the whole human fetal gut.The number of EC cells(EC cells with visible nucleus per visual field)at all period of gestation always decreased in an order from the mucosa of duodenum,jejunum,ileum,ap- pendix,colon and stomach respectivly.EC cells in the mucosa of antrum often po- ssessed long processes contacted with other types of glandular cells.The EC cells were open typed cells except those in the fundic mucosa.Grouped EC cells can also be seen in the mucosa of appendix and the intestinal glands.
出处 《解剖学报》 CAS CSCD 北大核心 1989年第3期282-285,共4页 Acta Anatomica Sinica
基金 国家自然科学基金
关键词 EC细胞 免疫组织化学 胎儿 EC cells Immunohistochemistry Human fetus
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参考文献3

  • 1王福圣,解剖学报,1988年,19卷,303页
  • 2黄威权,第四军医大学学报,1987年,8卷,220页
  • 3胡焕民,解剖学报,1981年,12卷,441页

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